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Clinical Trial Summary

Current guidelines have recommended classical bismuth-containing quadruple therapy including proton-pump inhibitor, bismuth, tetracycline, metronidazole as the empirical rescue therapy. However, tetracycline is clinically unavailable in China and the high frequency of adverse events of bismuth quadruple therapy often result in poor compliance, which limited the applicability of this recommendation. This study aimed to compare the efficacy and tolerability of a 14-day bismuth-containing quadruple rescue therapy in which tetracycline was replaced by doxycycline.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05874570
Study type Interventional
Source Shanghai Jiao Tong University School of Medicine
Contact
Status Recruiting
Phase Phase 4
Start date June 20, 2023
Completion date December 31, 2024

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