A Unique Regimen for Treatment of Helicobacter Pylori Infection

Status Recruiting

Clinical Trial Summary

The triple treatment including Proton pump inhibitor (PPI) -clarithromycin and amoxicillin or metronidazole was proposed 30 years ago at the first Maastricht conference to treat helicobacter pylori (H. pylori) infection and since that time, it has become the universal and standard treatment for helicobacter pylori.

However, the efficacy of this triple regimen has been seriously challenged, and they are gradually becoming ineffective

Clinical Trial Description

Growing rates of treatment failure are observed worldwide and the eradication rate of triple therapy has declined over the past few decades. Helicobacter pylori infection has become increasingly resistant to traditional first line treatment regimens because of emerging antibiotic resistance coupled with poor patient compliance with completing the treatment course that decrease H. pylori eradication rates .So there is a considerable interest in evaluating new antibiotic combinations and regimens . ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03491995
Study type	Interventional
Source	Tanta University
Contact	Sherief Abd-Elsalam, MD
Phone	00201147773440
Email	sheriefabdelsalam@yahoo.com
Status	Recruiting
Phase	Phase 3
Start date	April 1, 2018
Completion date	April 1, 2023

View Details

See also
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