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The Association of Endothelial Dysfunction and Cardiac Allograft Vasculopathy

Heart Transplantation Clinical Trial

Clinical Trial Summary

Progressive cardiac allograft vasculopathy (CAV) is a serious complication in long-term survivors after heart transplantation. Therefore, we hypothesize that CAV is a diffuse and progressive process, and endothelial function may play an important role in predicting clinical outcome after heart transplantation. Therefore, this single-blinded study is designed to evaluate endothelial function, microvascular flow response and morphology of coronary artery in cardiac allografts,

1. The simultaneous use of IVUS and Doppler wire instrumentation in different pharmacological stress;

2. Tl-201 SPECT (dipyridamole stress/rest); to evaluate the correlation of endothelial function, coronary morphology change and Tl-201 dipyridamole stress myocardial perfusion image.

Clinical Trial Description

n/a

Study Design

Observational Model: Defined Population, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00173914
Study type Observational
Source National Taiwan University Hospital
Contact Chii-Ming Lee, MD, phD
Phone 886-2-23123456
Email cmlee@ha.mc.ntu.tw
Status Recruiting
Phase N/A
Start date March 2003
View Details
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