Negative Venous Line Pressure in a Miniaturised Cardiopulmonary Bypass Circuit (CPB)

Heart Surgery Clinical Trial

Official title: Negative Venous Line Pressure in a Miniaturised Cardiopulmonary Bypass Circuit - the Influence of a Fenestrated Venous Cannula and Its Effect on Pump Flow

Status Completed

Clinical Trial Summary

Study to measure the ability of a 'fenestrated' venous line cannula to reduce the negative line pressure seen with kinetic-assist active venous drainage (KAVD) in a standard miniaturised cardiopulmonary bypass circuit and thereby increase the flow characteristics of the bypass pump.

Clinical Trial Description

To investigate whether a new venous drainage pipe (cannula) which has three sets of drainage holes (three-stage) compared with the standard two-stage cannula, or a three-stage which also has additional windows (fenestrations), can improve the drainage of blood into the circuit, reducing the negative pressure produced and increase the blood flow delivered to the patient. Patients who consent to participate will be randomly assigned to one of three types of venous cannula:

1. Standard venous cannulation with a two-stage venous cannula

2. The three-stage cannula (91437C, Medtronic)

3. The fenestrated three-stage cannula (MC2X, Medtronic) ;

Related Conditions & MeSH terms

• Heart Surgery

• NCT number: NCT03717649
• Study type: Interventional
• Source: University Hospital Plymouth NHS Trust
• Status: Completed
• Phase: N/A
• Start date: January 12, 2016
• Completion date: October 31, 2016