Heart Failure and Sleep Disordered Breathing

Heart Failure Clinical Trial

Official title:

Characteristics of Arrhythmia and Heart Rate Variability in Patients With Heart Failure and Sleep Disordered Breathing

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05892172
• Other study ID #: 2021020707
• Status: Recruiting
• Start date: June 28, 2023
• Est. completion date: April 30, 2024

Study information

• Verified date: May 2023
• Source: First Affiliated Hospital of Harbin Medical University
• Contact: Yihui Kong, M.D.
• Phone: 85555672
• Email: kongyihui[@]126.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to analyze and summarize the characteristics of arrhythmia and heart rate variability of Chinese patients with three different types of heart failure combined with sleep disordered breathing based on the clinical data, to provide new diagnosis and treatment ideas for domestic patients, and then to improve the prognosis of patients betterly.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 300
• Est. completion date: April 30, 2024
• Est. primary completion date: January 1, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

1. Age >18 years.

2. The diagnosis of heart failure conforms to the criteria of the Chinese Guidelines for the Diagnosis and Treatment of Heart Failure .

3. Echocardiography, dynamic electrocardiogram and polysomnography monitoring should be improved during the period of hospitalization.

4. Patients with sleep apnea have not received standard treatment.

Exclusion Criteria:

1. Patients undergoing cardiac surgery in the past 6 weeks.

2. Patients with acute decompensated heart failure or heart failure requiring oxygen therapy.

3. All patients with sleep apnea who receive standard treatment.

4. Patients who use pacemakers or implantable cardioverter defibrillators.

5. The patient did not complete the echocardiography, dynamic electrocardiogram, and polysomnography monitoring during hospitalization.

Related Conditions & MeSH terms

• Heart Failure
• Sleep Apnea Syndromes

Locations

Country	Name	City	State
China	Yihui Kong	Harbin	Heilongjiang

Sponsors (1)

Lead Sponsor	Collaborator
Yihui Kong

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	heart failure and sleep apnea	analyze and summarize the characteristics of arrhythmia and heart rate variability of Chinese patients with three different types of heart failure combined with sleep-disordered breathing based on the clinical data. Collection of clinical data: general clinical data, physical signs, post-admission inspection indicators, and treatment conditions of patients collected from the electronic medical record system. Echocardiographic data mainly included ejection fraction, left atrial anterior-posterior diameter, and interventricular septum thickness, which were in millimeters; electrocardiogram examination mainly included Diagnosis type of arrhythmia by dynamic, the overall standard deviation of normal sinus R-R interval (SDNN), the average standard deviation of normal sinus R-R interval throughout the recording period (SDANN), which were in a millisecond, etc; The type and severity of sleep-disordered breathing and Apnea hypopnea index were obtained by polysomnography.	24 hours