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Safety and Effectiveness of Left Bundle Branch Pacing in Patients With Cardiac Dysfunction and AV Block

Heart Failure Clinical Trial

Official title:
Safety and Effectiveness of Left Bundle Branch Pacing (LBBP) in Patients With Cardiac Dysfunction and AV Block

Clinical Trial Summary

This study is a multicenter, prospective, randomized study to assess if cardiac dysfunction patients with LVEF <50% and the estimated ventricular pacing percentage >40% with LBBP have the non-inferior safety and efficacy than CRT on patients' cardiac function and prognosis

Clinical Trial Description

Patients who meet the inclusion and exclusion criteria will be enrolled into the study. In the study, patients with cardiac dysfunction who met the enrollment criteria and will agree to participate in this trial will be 1:1 randomized to the LBBP group and the CRT group. Patients who were successfully implanted were enrolled for evaluation and follow-up. The primary end points of the study is the change of LVEF within 12 months post-implant in both LBBP Treatment Group and CRT Treatment Group ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05553626
Study type Interventional
Source First Affiliated Hospital of Wenzhou Medical University
Contact Weijian Huang, MD
Phone +86138-0669-1086
Email weijianhuang69@126.com
Status Not yet recruiting
Phase N/A
Start date September 2022
Completion date February 2025
View Details
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