Cancer Therapy Effects on the Heart

Status Recruiting

Clinical Trial Summary

Clinical Trial Description

Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) are commonly given to treat pediatric cancer, and carry a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death. However, current strategies for identifying patients who are at risk prior to the development of significant changes in heart function are limited. This study will focus on imaging markers of cardiac injury and dysfunction with the goal of developing improved diagnostic tests and treatment strategies. Cardiac remodeling, function, and tissue characteristics will be examined using cardiac MRI data in combination with standard cardiac assessments (by echocardiography, electrocardiograms, and cardiac MRI) to assess the cardiotoxic effects of cancer therapy. Analyses will be performed in a cohort of adolescents and young adults with a history of childhood cancer. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04262830
Study type	Observational
Source	University of California, San Diego
Contact	Hari Narayan, MD
Phone	8589665855
Email	hnarayan@rchsd.org
Status	Recruiting
Phase
Start date	September 30, 2019
Completion date	September 30, 2029

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See also
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Cancer Therapy Effects on the Heart — CTEH

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms