Early Detection of Cardiac Toxicity in Childhood Cancer Survivors

Status Terminated

Clinical Trial Summary

To evaluate cardiac MRI and/or serum biomarkers for detecting cardiac cardiac toxicity in children who received anthracycline based chemotherapy (ABC).

Clinical Trial Description

Cardiac toxicity is a significant potential complication for patients receiving anthracycline chemotherapy. Cells in the cardiovascular system have limited regenerative capability, making them susceptible to long term adverse effects from these chemotherapeutic agents. The ability to detect subclinical changes in cardiac function will allow clinicians to use proven treatments to prevent further progression in this vulnerable population. The current standard testing uses echocardiography, which is not as sensitive as cardiac MRI or serum biomarkers. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03038997
Study type	Observational
Source	Children's Research Institute
Contact
Status	Terminated
Phase
Start date	November 2014
Completion date	March 11, 2018

View Details

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