Heart Failure Clinical Trial
Official title:
Responders and Quadripolar LV Lead in CRT
The purpose of this study is to observe the evolution of the CRTD system with left quadripolar lead, in terms of electrical parameters in all pacing configurations and to evaluate the impact on the clinical outcome.
Cardiac resynchronization therapy (CRT) is limited by a high proportion of non-responders.
Pacing activation from proximal area with a left quadripolar lead might improve the
depolarization pattern.
To explore the effect of CRT pacing on cardiac activity, the investigators will enroll
approximately 180 patients who already underwent CRT-D implantation with a quadripolar LV
lead.
After implant, as clinical practice, the device will be programmed with distal LV pacing
configuration, after 6 months in patient non-responders to CRT therapy the pacing
configuration will be changed (proximal configuration).
After 12 months in patients non-responders will be changed the pacing configuration again,
choosing, if it is possible, a multi point pacing (pacing activation from multiple separated
left ventricular (LV) sites).
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Observational Model: Case-Only, Time Perspective: Prospective
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