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A Study Evaluating Biomarkers in Participants With Heart Failure (MK-0000-344)

Heart Failure Clinical Trial

Official title:
A Clinical Trial to Evaluate Circulating and Imaging Biomarkers in Heart Failure Patients

Clinical Trial Summary

The aim of this 2-part study is to assess B-type natriuretic peptide (BNP) as well as other circulating and imaging biomarkers in myocardial function. Part 1 assesses biomarker levels in healthy participants and participants with cardiac dysfunction. Part 2 assesses BNP and other circulating biomarker levels, and performs imaging in participants with cardiac dysfunction who continued from Part 1. The primary hypothesis is that compared to healthy participants, biomarker levels are elevated in participants with mild/moderate and severe cardiac dysfunction.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02364752
Study type Interventional
Source Merck Sharp & Dohme Corp.
Contact
Status Withdrawn
Phase Phase 1
Start date September 2015
Completion date November 2016
View Details
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