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Stem Cells and Resynchronization Cardiac — RCT and SCT  

Heart Failure Clinical Trial

Official title:
Stem-Cells and Heart Failure in Several Ethiologies. Alternative Indication With Cardiac Resynchronization

Clinical Trial Summary

Same patients with dilated myocardiopathies with large areas of fibrosis has not been as successful after Cardiac Resynchronization Therapy, for Heart Failure patients in functional class III or IV. Therefore the investigators have decided to associate the Stem-Cell implant with Cardiac Resynchronization Therapy in these patients.

Clinical Trial Description

About 120cc of blood are collected from the iliac bone marrow under epidural anesthesia.In the cell therapy lab this blood is harvested and mononuclear cells are separated.This procedure takes roughly 4 hours.After dilution the mononuclear cells are injected into the cardiac muscles with fibroses area through 20 shots.This procedure is indicated for patients with cardiac ischemia and left ventricular dysfunction(desynchrony), on whom all the others known therapies have failed. ;

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00800657
Study type Interventional
Source Instituto de Molestias Cardiovasculares
Contact Oswaldo Tadeu Greco, PhD
Phone 55-17-3203-4000
Email oswaldogreco@terra.com.br
Status Recruiting
Phase Phase 1
Start date November 2008
Completion date December 2011
View Details
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