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Efficacy and Safety of Relaxin for the Treatment of Acute Heart Failure — RELAX-AHF  

Heart Failure, Congestive Clinical Trial

Official title:
A Phase II/III, Multicenter, Randomized, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Relaxin in Subjects With Acute Heart Failure

Clinical Trial Summary

Different doses of relaxin will be compared to placebo to determine efficacy and safety for the treatment of patients hospitalized with acute heart failure

Clinical Trial Description

This is an international, randomized, double-blind, placebo-controlled, Phase II/III trial of intravenous recombinant relaxin for the treatment of signs and symptoms in patients hospitalized for acute decompensated heart failure. The Phase II pilot study has completed; the Phase III main portion of the trial is ongoing. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00520806
Study type Interventional
Source Corthera, Inc.(formerly BAS Medical, Inc.), a member of the Novartis group of companies
Contact
Status Completed
Phase Phase 2/Phase 3
Start date October 2007
Completion date September 2012
View Details
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