Heart Failure, Congestive Clinical Trial
Official title:
Evaluation of Safety and Feasibility Magnetic Resonance Imaging of the Heart at 1.5 Tesla In Patients With Implantable Cardioverter Defibrillators
To evaluate short-term and long-term effects by MR imaging on the technical and functional status of implantable cardioverter defibrillators.
The presence of an implantable cardioverter defibrillators (ICD) is currently considered an
absolute contraindication to MR imaging, and most patients with PM are excluded from having
MRI. As a result from studies such as MADIT I, MADIT II, SCDHeft etc. the number of patients
with ICDs has been continuously growing over the past years, ans this development will
continue.
The aim of this study is to develop a strategy for safe performance of MR imaging at 1.5T,
which included restriction of specific absorption rate (SAR) values to minimize the risk of
lead heating, and ICD reprogramming to avoid interference from time varying gradient fields.
The safety of this approach is then evaluated in a large group of ICD patients including
assessment of potential myocardial thermal injury by measuring serum troponin I and pacing
capture thresholds, and performing a follow-up 6 weeks after MR imaging to evaluate
long-term effects.
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Observational Model: Defined Population, Time Perspective: Longitudinal
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