Heart Diseases Clinical Trial
Official title:
Health Disparities and CVD: Admixture Mapping in the Jackson Heart Study
Heart disease and stroke disproportionately affect African Americans in the United States. These conditions are likely caused by both environmental and genetic factors. This study will attempt to identify specific genes of African and European ancestral origins that may influence the development of heart disease in African Americans.
African Americans have a high risk of developing heart disease and stroke, and are more
likely to die from heart-related illnesses than other racial and ethnic groups. A large
majority of African Americans are descendants of both African and European ancestors who
mixed five to six generations ago. Because only a few generations have passed since that
time, it is still possible to identify specific genes, the basic units of heredity, as being
either African or European in origin. This is a sub study of the Jackson Heart Study, which
is examining the environmental and genetic factors that influence the development of heart
disease in African Americans. In this study, researchers will examine genes from
participants in the Jackson Heart Study to identify specific African and European genes that
influence the development of heart disease in African American men and women.
This study will use genetic samples from individuals participating in the Jackson Heart
Study. There will be no study visits for participants. Study researchers will examine the
genetic samples and identify specific African and European genes that may influence the
development of heart disease, high blood pressure, lipid disorders, left ventricular
hypertrophy, and low birth weight.
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