Quantification of Cerebral Perfusion by Contrast-enhanced Ultrasound

Status Completed

Clinical Trial Summary

Transcranial contrast-enhanced ultrasound for evaluation of cerebral blood flow during pediatric cardiac surgery. This study is aimed as a feasibility study prior to conducting a lager prospective clinical trial including neurologic and developmental outcome measures.

Clinical Trial Description

The cerebral perfusion of infants with congenital heart defects is a critical determinant during cardiac surgery. The majority of these interventions is performed during deep or moderate hypothermia (25-32°C) with reduced blood flow of the heart-lung-machine (HLM). Assuming a symmetrical anatomy of the cerebral arteries (C. Willisii) a single vessel (T. brachiocephalicus) is then supplying the cerebral blood flow. Using contrast-enhanced ultrasound the cerebral blood flow will be assessed during cardiac surgery interventions. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03215628
Study type	Interventional
Source	University of Erlangen-Nürnberg Medical School
Contact
Status	Completed
Phase	N/A
Start date	July 4, 2017
Completion date	August 30, 2021

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Quantification of Cerebral Perfusion by Contrast-enhanced Ultrasound During Neonatal Heart Surgery — TCEUS

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms