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Hearing Loss clinical trials

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NCT ID: NCT01150305 Completed - Hearing Impairment Clinical Trials

Epidemiology of Non-syndromic Dominant Deafness

SURDOM
Start date: April 2009
Phase: N/A
Study type: Observational

Hearing impairment is a common disorder that affects at least 7% of individuals in our countries. Even the causes of hearing impairment are numerous, genetic causes represent the main factor of sensorineural deafness. Among hereditary non-syndromic deafness autosomal-dominant inheritance is observed in about 10-20% of the cases. These forms of deafness are usually post-lingual and progressive. To date more than 41 chromosomal localisation and 21 genes associated to non syndromic dominant deafness have been described. It represents an extreme genetic heterogeneity making difficult the studies of these forms of hearing impairment. But, genetic diagnostic testing is crucial in these cases. Indeed, therapeutic research are in the way to prevent the progression of the disorder. The aim of this work is to establish the prevalence of the different genes involved in these forms of deafness.

NCT ID: NCT01139281 Completed - Hearing Loss Clinical Trials

The Protective Effect of Ginkgo Biloba Extract on Cisplatin-induced Ototoxicity in Humans

Start date: June 2007
Phase: Phase 2
Study type: Interventional

The proposal of this study was to evaluate in human beings, using distortion product otoacoustic emission (DPOAE) test, the action of ginkgo biloba extract (GBE761)as a possible ear protective against cisplatin (CDDP) induced hearing loss.

NCT ID: NCT01132092 Completed - Clinical trials for Subjects With Hearing Loss (15 Subjects)

The Normal Standard of Brainstem Auditory Evoked Potential in Adults Using a New Device

Start date: n/a
Phase: N/A
Study type: Observational

There are no differences between the exams made with the new device,that evaluates the hearing, and the device gold standard, that is widely used in clinics and hospitals.

NCT ID: NCT01108406 Completed - Hearing Loss Clinical Trials

Long Term Safety of the Sonitus SoundBite System

Start date: April 2010
Phase: N/A
Study type: Interventional

The objective of this study is to assess the long-term safety and quality of life improvement of the Sonitus SoundBite Hearing System.

NCT ID: NCT01102621 Completed - Hearing Loss Clinical Trials

Hearing Loss and Complaint in Patients With Head and Neck Cancer Treated With Radiotherapy

Start date: January 2005
Phase: N/A
Study type: Observational

Hypothesis: Treatment for head and neck tumors often involve methods that affect the auditory system and cause hearing loss. Neck dissection negatively impacts the lymphatic drainage, chemotherapy uses ototoxic drugs, radiotherapy affects blood flow and tissue radiation is toxic to the ear and may lead to hearing losses of various types and degrees. Objective: To investigate occurrences of hearing loss and complaints among patients with head and neck tumors who underwent radiotherapy. Study design: Prospective, case-control study. Setting: Tertiary care center hospital. Subjects and Methods: 282 subjects were evaluated, 141 with head and neck tumors and 141 as an age-matched control group. The controls had never undergone oncological treatment that put their hearing at risk. All subjects underwent audiological evaluation, including the HHIE questionnaire, pure tone audiometry, speech audiometry and immittance audiometry. The radiation dose received by the auditory system was calculated based on the percentage of the external auditory canal included in the radiation field.

NCT ID: NCT01092910 Completed - Clinical trials for Mild to Severe Sensorineural Hearing Loss

Esteem Totally Implantable Hearing System

Start date: January 2008
Phase: N/A
Study type: Interventional

To evaluate the safety and efficacy of the Esteem Totally Implantable Hearing System in subjects suffering from mild to severe hearing loss.

NCT ID: NCT01072409 Completed - Hearing Loss Clinical Trials

Clinical Evaluation of the Nucleus 5 Cochlear Implant (CI) System

Start date: March 2010
Phase: N/A
Study type: Interventional

To evaluate the performance of the Nucleus 5 Cochlear Implant System.

NCT ID: NCT01059838 Completed - Hearing Loss Clinical Trials

Speech Perception for Children With Cochlear Implants

Start date: October 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether speech recognition in noise can be improved by the addition of a special listening program to the sound processor. Thus we propose to assess speech perception in noise for pediatric cochlear implant patients using both their everyday listening program as well an ASC program.

NCT ID: NCT01054378 Completed - Neck Pain Clinical Trials

Diaphragmatic Movement Before and After Stellate Ganglion Block : A Ultrasonographic Study

Start date: January 2010
Phase: Phase 4
Study type: Interventional

The temporary diaphrgmatic dysfunction will occur after stellate ganglion block(SGB) and will be easily detected by M-mode ultrasonography

NCT ID: NCT01038336 Completed - Clinical trials for Hearing Loss, Noise-Induced

Hearing Loss Prevention for Veterans

HLPP
Start date: May 2011
Phase: N/A
Study type: Interventional

Hearing loss is the most prevalent service-connected disability in the VA. It causes communication difficulties, which contribute to isolation, frustration and depression. A major cause of hearing loss is from exposure to high levels of sound, and is referred to as Noise Induced Hearing Loss (NIHL). Veterans have inevitably been exposed to high levels of sound during military service, and even though they may not yet have NIHL, their ears have been damaged. Continued noise exposure in civilian life will result in NIHL. However, it can easily be prevented by avoiding noise or using hearing protection. Most people are unaware that noise damages hearing, and even when they are, they do not use hearing protection. In this study we will use a randomized controlled trial to evaluate the short- and long-term effectiveness of two forms of education about NIHL that we have developed for Veterans. One is a computerized program; the other is a Hearing Conservation Brochure