Clinical Trials Logo

Hearing Loss, Noise-Induced clinical trials

View clinical trials related to Hearing Loss, Noise-Induced.

Filter by:

NCT ID: NCT06058767 Recruiting - Hearing Loss Clinical Trials

Preschool Hearing Screening

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

Children who are deaf or hard-of-hearing (D/HH) are at risk of speech and language delays, which can be mitigated through early identification and intervention. Identifying hearing loss (HL) during preschool is crucial, but the most effective hearing screening method for preschoolers remains uncertain. The purpose of this study is to learn whether, compared to the gold-standard two-stage Pure-tone audiometry (PTA) + otoacoustic emissions (OAE) screening (TS-PO), single-stage OAE (SS-O) screening alone is not inferior at identifying hearing loss when performed in a community-based preschool setting. This study holds the potential to improve early hearing loss detection and intervention among D/HH children, reducing the likelihood of speech and language delays. A diverse group of 28,000 preschool-age children across community-based preschool centers will be recruited. The intervention involves all subjects undergoing both PTA and OAE screening, with the order determined through randomization. Children who show potential hearing issues based on screening results or teacher concerns will receive further testing to determine the final hearing outcome. Group allocation will be post-hoc, based on their screening results. In addition to the primary objective, the study will compare other hearing screening measures and outcomes between the two methods (TS-PO and SS-O). This approach aims to reflect the real-life effectiveness of hearing screening in a diverse population. Ultimately, the study seeks to provide insights into an optimal hearing screening method that could prevent speech and language delays among D/HH children.

NCT ID: NCT05636488 Not yet recruiting - Clinical trials for Noise Induced Hearing Loss

Determination of the Effects of Noise Level in the Operating Room

Start date: December 1, 2022
Phase:
Study type: Observational

The goal of this observational study is to learn about effects of noise in healthy patients undergoing elective surgery.

NCT ID: NCT05511753 Not yet recruiting - Electroacupuncture Clinical Trials

The Effect of Acupuncture on Patients With Noise-induced Hearing Loss

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

In an era of advanced industry and commerce, working in a noisy environment is one of the most important risk factors for hearing damage, especially among young and middle-aged people. Although acupuncture has been widely used to treat otology-related diseases, such as tinnitus, dizziness, and sudden deafness, there are few studies on the effect of noise-induced hearing loss.

NCT ID: NCT05468567 Recruiting - Hearing Loss Clinical Trials

Three-dimensional Perception of Sounds in Military With Acoustic Trauma

SPHEAR
Start date: March 31, 2023
Phase:
Study type: Observational

Spatial hearing capacities of soldiers with acoustic trauma are evaluated in ENT consultations with routine tests (i.e. tonal audiometry, voice audiometry). While the results conclude that soldiers with acoustic trauma have sufficient abilities to carry out professional missions, soldiers report recurring complaints of sound localization (spatial hearing), i.e. difficulties in identifying the position of sound sources in their environment. However, there is currently no objective test to identify and objectify these complaints of spatial hearing. The investigators have developed a new approach (SPHERE) based on virtual reality and 3D motion tracking, allowing us to evaluate and record the spatial hearing performance of subject with hearing deficit. This system allowed us to highlight localization deficits in three-dimensional space. This project explores and quantifies the spatial hearing impairments of soldiers with acoustic trauma. The quantification of the spatial hearing capacities will allow to define a specific rehabilitation strategy of spatial hearing deficits.

NCT ID: NCT05086276 Completed - Clinical trials for Hearing Loss, Sensorineural

FX-322 in Adults With Acquired Sensorineural Hearing Loss

Start date: October 12, 2021
Phase: Phase 2
Study type: Interventional

This is a Phase 2, prospective, randomized, double-blind, placebo-controlled, single-dose, multicenter study to evaluate the efficacy of FX-322, administered by intratympanic injection, in adults with acquired sensorineural hearing loss (SNHL).

NCT ID: NCT05076344 Recruiting - Hearing Loss Clinical Trials

Understanding the Consequences of Recreational Noise Exposure

Start date: May 19, 2022
Phase:
Study type: Observational

The aim of this study is to determine whether measures derived from Magnetic Resonance Imaging (MRI) scans, and clinical and behavioural measures of hearing loss, in the peripheral and central auditory system (ranging from the cochlear nerve through the auditory brainstem to the auditory cortex) are associated with age and history of noise exposure in otherwise healthy adult humans.

NCT ID: NCT04832230 Recruiting - Acoustic Trauma Clinical Trials

Study of Diagnostic Biomarkers of Acute Acoustic Trauma

BIOTSA
Start date: April 15, 2021
Phase:
Study type: Observational

Every year, more than two thousand acute acoustic trauma occur in France, equally between the military and the civilian environment. Currently, acute acoustic trauma is a pathology with no specific validated treatment, and it is the cause of many handicapping situations. Improving the future of patients requires a better understanding of the neurophysiological mechanisms of noise-induced hearing impairment. They are multiple and pure tone audiometry, the only reference examination, does not allow to differentiate them. Moreover, in the aftermath of acute acoustic trauma, pure tone audiometry tends to improve spontaneously, but this recovery is misleading, as a number of studies in animals have shown that irreversible lesions remain. The hypothesis of this study is that it is possible to identify new entities, specific to the type of cochlear lesions, in order to clarify the diagnosis of acute acoustic trauma. These entities will be identified by the evaluation of noise-induced hearing impairment via a combination of molecular (proteomic and genomic), physiological and behavioral data. These diagnostic details may then be used to improve prevention or therapy.

NCT ID: NCT04804982 Completed - Acoustic Trauma Clinical Trials

Study of the Use of Hearing Protection Equipment in the Occurence of Acute Acoustic Trauma in the Army

QPROTEC
Start date: March 30, 2021
Phase:
Study type: Observational

Each year, military epidemiological surveillance counts approximately 1,000 acute acoustic injuries. Most are caused by exposure to weapon noise during training sessions while military personnel are provided with hearing protection. Several hypotheses could explain the occurrence of acute acoustic trauma despite wearing protections: - A lack of practices or knowledge about the use of hearing protection equipment that could facilitate the occurrence of acute acoustic trauma (improper fitting, use of an inappropriate type of protection, dropping of protectors, inappropriate removal) - A failure to seal the external ear canal due to an inappropriate plug size. These hypotheses will be explored using a questionnaire distributed to a population of Army soldiers training to shoot. The main objective is to determine the predictive factors corresponding to practices or knowledge related to the use of hearing protection equipment in the occurrence of acute acoustic trauma in a population of Army soldiers.

NCT ID: NCT04774250 Terminated - Clinical trials for Hearing Loss, Noise-Induced

Noise-Induced Hearing Loss-Acute Exposure Treatment (UA)

PINIHL-AET
Start date: November 10, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of zonisamide (ZNS) for the treatment of noise-induced hearing loss in adults.

NCT ID: NCT04768569 Terminated - Clinical trials for Hearing Loss, Noise-Induced

Noise-Induced Hearing Loss-Acute Exposure Treatment

PINIHL-AET
Start date: October 4, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of zonisamide for the treatment of noise-induced hearing loss in adults.