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Fractionated 1927-nm Non Ablative Thulium Laser in Treating Post Inflammatory Hyperpigmentation

Healthy Clinical Trial

Official title:
Efficacy and Safety of the Fractionated 1927-nm Non Ablative Thulium Laser in Treating Post Inflammatory Hyperpigmentation in Skin Phototypes IV-VI

Clinical Trial Summary

To study the effect of fractionated 1927-nm non ablative thulium laser in reduction of post inflammatory hyperpigmentation (PIH) using a validated and reproducible model for studying PIH. - Determine if there is aa reduction in PIH in patients treated with three (3) monthly sessions of fractionated 1927-nm non ablative thulium laser - Determine if there is efficacy of post-procedure clobetasol propionate 0.05% ointment in the management of PIH - Determine the histological and molecular changes that occur with laser and laser plus topical steroid treatment compared to untreated skin

Clinical Trial Description

The design of the study consists of a total of six visits including one initial screening visit within 107-127 days depending on the scheduling of your screening and subsequent visits. Assessments such as visual examination, photography, Investigatory Global Assessment (IGA) of pigmentation and erythema; Colorimetry; and Diffuse Reflectance Spectroscopy of the intended treatment area will be conducted at Visits 1-5. Optional biopsies will be taken at various time points. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06149780
Study type Interventional
Source Henry Ford Health System
Contact Fanar Razoky, Bachelors
Phone 313-694-1923
Email frazoky1@hfhs.org
Status Recruiting
Phase N/A
Start date November 15, 2023
Completion date August 30, 2026
View Details
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