Mechanisms of Exercise-Induced Hypoalgesia

Healthy Clinical Trial

Official title:

Mechanisms of Exercise-Induced Hypoalgesia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06050889
• Other study ID #: 6
• Status: Completed
• Phase: N/A
• Start date: November 14, 2023
• Est. completion date: April 19, 2024

Study information

• Verified date: April 2024
• Source: University of Central Florida
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Exercise-Induced Hypoalgesia (EIH) is a lessening of pain sensitivity in response to an acute bout of exercise. Limited research has examined the effects of expectations on EIH during a dynamic resistance training during different intensities. Therefore, the purpose of this study is to examine the effects of positive and negative expectations on EIH.

Description:

Individuals who meet the eligibility criteria and consent to participate will attend one testing session that is approximately one hour. Baseline Pressure Pain Threshold will be measured followed by random assignment to one of four study arms.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: April 19, 2024
• Est. primary completion date: April 19, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 60 Years

Eligibility

Inclusion Criteria:

• Pain Free

Exclusion Criteria:

• Non-English speaking

• Regular use of prescription pain medications

• Current or history of chronic pain condition

• Currently taking blood-thinning medication

• Any blood clotting disorder, such as hemophilia

• Systemic medical condition known to affect sensation, such as uncontrolled diabetes or neurological conditions

• Not physically ready to exercise without a medical exam as indicated by the Physical Activity Readiness Questionnaire Plus (PAR-Q+)

• Not have had Surgery, injury, or fracture within the past 6 months

Related Conditions & MeSH terms

• Healthy

Intervention

Other:
• Positive Expectations Instructional Set
Participants randomly assigned to this instructional set will be told, "You will be completing an intervention known to be effective for some people with shoulder pain. We expect this will make you less sensitive to the pressure applied to your shoulder and thigh and you will require more pressure than what was previously necessary to experience pain."
• Negative Expectations Instructional Set
Participants randomly assigned to this instructional set will be told, "You will be completing an intervention which is not effective for some people with shoulder pain. We expect this will make you more sensitive to the pressure applied to your shoulder and thigh and you will require less pressure than what was previously necessary to experience pain."

Locations

Country	Name	City	State
United States	University of Central Florida	Orlando	Florida

Sponsors (1)

Lead Sponsor	Collaborator
University of Central Florida

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pressure Pain Threshold	Pressure Pain Threshold will be applied with a digital algometer before and after the exercise intervention.	Change from baseline immediately after exercise