Healthy Clinical Trial
— IEQ-HUMOfficial title:
The Effect of the Indoor Environmental Quality (IEQ) on Cognition and Health
The goal of this study is to learn about the effect of heat and humidity on cognition and health. The main question[s] it aims to answer are: type of study: interventional participant population: 20-40years, both gender, healthy Participants will be exposed for 4 different sessions of 8 hours at a time, to 32˚ C or 25˚ C in combination with relative humidity of 30 %RH or 70 %RH.
Status | Recruiting |
Enrollment | 26 |
Est. completion date | June 1, 2024 |
Est. primary completion date | May 30, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 20 Years to 40 Years |
Eligibility | Inclusion Criteria: - BMI between 18.5-26 kg/m2 - Age between 20-40 years - Proficient with the English language in both verbal and written form - Healthy; no illness or disease or prescribed medication within the last 3 months - Steady dietary and sleeping habits - Regularly physically active (i.e., regularly active but less than 3 times a week for less than 2 hours per session at moderate intensity) - Non-smoker or person who quit smoking more than five years ago - Reside in the Netherlands (or surrounding countries) for at least 6 months Exclusion Criteria: - Subjects with cardiac problems and cardiovascular diseases, such as angina pectoris, cardiac infarction, and arrhythmias - Subjects with any medical condition requiring treatment and/or medication (except oral contraceptives) that might interfere with the investigated parameters E.g., Extreme chronotype, colour blindness, epilepsy - Subjects with a disorder or disease (Parkinson, Attention Deficit Hyperactivity Disorder (ADHD), Alzheimer, diabetes, cardiovascular disorder, respiratory impairments (for example asthma), hypertension, obesity, or any other condition that can impair the lung function), or Raynaud's phenomenon - Subjects with abnormal diet and sleeping patters and/or abnormal body weight (weight gain or loss >3kg in the past month) - Subjects who recently participated in other interventional biomedical study within 1 month prior to screening visit - Subjects, who do not want to be informed about unexpected medical findings, or do not wish that their treating physician will be informed, cannot participate in this study - Subjects with previous covid infection in the past 3 months or any subject with persistent long covid symptoms that may have caused ongoing loss of or altered sense of smell - Subjects who had severely altered sleep patterns in the past year - Subjects employed with night shift work within the past year - Subjects who consume more than two standard drinks of alcohol per day - Subjects who consume more than two standard drinks of coffee per day - Subjects who are pregnant |
Country | Name | City | State |
---|---|---|---|
Netherlands | Maastricht University | Maastricht |
Lead Sponsor | Collaborator |
---|---|
Maastricht University Medical Center |
Netherlands,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Room Temperature (C) | Environmental measures are measured continuously using temperature specific sensors in the room | 1 month | |
Other | Humidity (%) | Environmental measures are measured continuously using humidity specific sensors in the room | 1 month | |
Primary | Cognition | Using a tablet based cognitive test battery | 1 month | |
Secondary | Heart Rate (bpm) | Heart Rate measured using Polar heart rate belt in (bpm) with RR and ECG data extracted | 1 month | |
Secondary | Blood pressure (mmHg) | Blood pressure - both systolic and diastolic pressures measured hourly using an automated blood pressure monitor and cuff | 1 month | |
Secondary | Metabolic Rate (ml O2//min/kg) | Metabolic rates measured through whole room calorimetry | 1 month | |
Secondary | Skin Temperature (C) | Skin temperature measured using thermochron (ibuttons) at multiple sites | 1 month | |
Secondary | Body Core Temperature (C) | Core Temperature measured via telemetric pill ingested in the morning | 1 month |
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