Healthy Clinical Trial - Characterization of Gastric Evoked Potentials

Status Recruiting

Clinical Trial Summary

This is an exploratory study that will determine and standardize how best to record gastric evoked potentials (GEPs) elicited by a non-invasive method of brain stimulation (Transcranial Magnetic Stimulation, TMS), by optimizing the TMS parameters and cortical sites necessary to evoke GEPs.

Clinical Trial Description

The overall goal of this exploratory study is to determine the optimal conditions to elicit gastric evoked potentials (GEPs) with Transcranial Magnetic Stimulation (TMS). Aim 1: Determine the optimal stimulation parameters and the optimal location for eliciting GEPs in cortical motor areas. Aim 2: Determine whether various modes of repetitive TMS (rTMS) neuromodulation targeted to GEP hotspots shape gastric motor responses to a water load. The investigators will record some clinical, demographic, and autonomic data (i.e. EKG) in our enrolled subjects. Secondary analyses will use these variables as covariates to investigate any systematic impact on the measures from Aims 1 and 2. ;

Study Design

Related Conditions & MeSH terms

Healthy

Clinical Trial Details

NCT number	NCT05924009
Study type	Interventional
Source	University of Pittsburgh
Contact	Paul HM Kullmann, PhD
Phone	412-647-1533
Email	phmk@pitt.edu
Status	Recruiting
Phase	N/A
Start date	July 17, 2023
Completion date	July 2026

View Details

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