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NCT05863039 Clinical Trial

Resistance Training With Blood Flow Restriction

Healthy Clinical Trial

Official title:
Resistance Training With Blood Flow Restriction for the Lower Extremity Muscles

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05863039
Other study ID # 14083
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date November 1, 2022
Est. completion date September 30, 2026

Study information
Verified date November 2023
Source University of Oklahoma
Contact Hugo Pereira, PhD
Phone 4053252773
Email hugomax@ou.edu
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Blood flow restriction associated with resistance training is suggested to potentiate increases in muscular strength and hypertrophy. This study will compare the effects of resistance training associated with blood flow restriction with a regular resistance training program. Findings of this project will provide important information regarding a promising intervention to potentiate muscle performance.

Description:

The purpose of this study is to determine alterations in motor unit behavior of the tibialis anterior muscles after a resistance exercise program associated with blood flow restriction. Our working hypothesis is that blood flow restriction to working muscles will induce greater changes in muscle activation, lean mass and muscle size compared with a training at same intensity without blood flow restriction.

Recruitment information / eligibility
Status Recruiting
Enrollment 60
Est. completion date September 30, 2026
Est. primary completion date May 31, 2025
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 50 Years
Eligibility Exclusion Criteria: - presence of neurological diseases, - presence of metal implants or joint replacement - any restriction to perform physical activity - pregnancy

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Blood flow restriction
Strength training of the lower leg muscles using blood flow restriction
• Regular training type 1
Strength training of the lower leg muscles using high loads
• Regular training type 2
Strength training of the lower leg muscles using low loads

Locations
Country Name City State
United States University of Oklahoma Norman Oklahoma

Sponsors (1)
Lead Sponsor Collaborator
University of Oklahoma

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Force Force of the lower leg muscles using a custom made ergometer 10 sessions (up to 6 weeks)
Secondary Body composition dual x-ray absorptiometry (DEXA) will be used to assess body composition Start and end of the protocol
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