VR, Visio-tactile Stimulation and Embodiment

Healthy Clinical Trial

Official title:

Creating Embodiment in Virtual Reality: A Pilot Study Evaluating Visio-tactile Stimulation and Feasibility

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05836038
• Other study ID #: HM&E123
• Status: Not yet recruiting
• Phase: N/A
• Start date: June 1, 2024
• Est. completion date: June 1, 2025

Study information

• Verified date: May 2024
• Source: Tufts University
• Contact: Nancy Baker, ScD
• Phone: 617 627-5562
• Email: nancy.baker[@]tufts.edu
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Investigators will evaluate the feasibility of "puppeting" a virtual hand with the opposite hand in increasing complex movements and the effect of visio-tactile stimuli on embodiment to determine if it is a necessary part of the process.

Description:

Embodiment refers to a subjective experience where a person views a simulated body and its properties are experienced as if they were the person's own biological body (1). Embodiment is notably seen in the rubber hand illusion (2): a rubber hand is made to substitute for the real hand using visio-tactile stimulation to connect the rubber hand to the participant. In visio-tactile stimulation, the real hand is hidden from view and the rubber hand is positioned where the real hand should be. Both hands are simultaneously stroked while the participant views the rubber hand. Within a short time, the rubber hand "feels" touch and pain, independent of the real hand.

In this study investigators will evaluate the ability to enable embodiment in a virtual reality environment. After providing background information, participants will then complete the "Real Hand Session" of the Study Protocol (See below) using their real hand to move the same side virtual hand (e.g. left real hand movements will move left virtual hand). Participants will complete Usability and Embodiment /Presence surveys After the Actual Protocol, participants in the VTS group will receive visio-tactile stimuli. They will see their virtual hand touched while simultaneously feel their opposite real hand touched in the same pattern. Participants in the NoVTS will spend the same amount of time looking at their virtual hand without the touching (~1 minute).

For the "Puppet Session" participants will complete the same tasks as the "Real Hand Session"(See Below) but movement of the real hand will "puppet" the opposite virtual hand (right real hand movements will move left virtual hand). After completing the session participants will complete Usability and Embodiment /Presence surveys

Study Protocol Sessions.(20 to 30 minutes). All take place in the virtual environment Hand Movement- Press a 36-button sequence 4x Bilateral Task - "Catch" 36 "fireflies" with both hands 4x. Unilateral Task - "Catch 36 "fireflies" with one hand 4x. Avoidance Task - Press a 36-button sequence. A "dangerous" virtual obstacle (e.g., sawblade) will be placed in the path of the virtual hand during some of the trajectories. Investigators will see how far from the most efficient trajectory participants moves to avoid the object

Hypotheses H1: Participants will demonstrate a greater sense of embodiment with visio-tactile stimuli (VTS) than without visio-tactile stimuli (NoVTS) H1a: Participants in the VTS group will report higher levels of embodiment than those in the NoVTS group.

H1b: Participants will demonstrate significantly better motor performance in the VTS group than the NoVTS group.

H1c: Participants in the VTS group will demonstrate greater avoidance of "dangerous items" than those in the NoVTS group H1d: Participants in the VTS group will report better usability of the embodied virtual hand than those in the NoVTS group.

H2: Motor Performance of the "Puppeted" virtual hand will be similar to the "Actual" virtual hand.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 30
• Est. completion date: June 1, 2025
• Est. primary completion date: December 1, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• • 30 adult participants (18+)

• Right Handed

Exclusion Criteria:

• Seizure, loss of awareness, or other symptom linked to an epileptic condition in the last 5 years

• Blind;

• Unable to use hands to reach and grasp items

• Implanted medical device such as a pacemaker, defibrillator, or hearing aid.

• Contagious disorder on the face (such as pink eye) that could be transmitted via the VR head set or has open areas on the face or head that would come in contact with the headset;

• Unable to understand and respond to English

Related Conditions & MeSH terms

• Healthy

Intervention

Behavioral:
• Visio-Tactile Stimulation
They will see their virtual hand touched while simultaneously feel their opposite real hand touched in the same pattern.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Tufts University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Motor Performance - Speed	We will track and store participant movements during each task via the VR headset. These movements will be downloaded and processed to calculate speed	Through study completion, 1 day
Primary	Motor Performance - Velocity	We will track and store participant movements during each task via the VR headset. These movements will be downloaded and processed to calculate velocity	Through study completion, 1 day
Primary	Motor Performance - Precision	We will track and store participant movements during each task via the VR headset. These movements will be downloaded and processed to calculate Precision	Through study completion, 1 day
Primary	Motor Performance - Trajectory	We will track and store participant movements during each task via the VR headset. These movements will be downloaded and processed to calculate trajectory	Through study completion, 1 day
Primary	Motor Performance - Path Length	We will track and store participant movements during each task via the VR headset. These movements will be downloaded and processed to calculate path length	Through study completion, 1 day
Primary	Motor Performance - Time to Target	We will track and store participant movements during each task via the VR headset. These movements will be downloaded and processed to calculate Time to target	Through study completion, 1 day
Primary	Motor Performance - Error rate	We will track and store participant movements during each task via the VR headset. These movements will be downloaded and processed to calculate error rate	Through study completion, 1 day
Primary	Embodiment	Participants perception of immersion during VR experience: Using Peck's Embodiment Scale (16 items scored on a 7 point likert scale with a final score between 1 and 7 with a higher score indicating greater emobidment) and the IPQ Presence questionnaire (14 items on a 7 point likert scale with a higher score indicating greater embodiment)	Through study completion, 1 day
Primary	Presence	Participants perception of immersion during VR experience: IPQ Presence questionnaire (14 items on a 7 point likert scale with a score between 7 and 98 and a higher score indicating greater presence)	Through study completion, 1 day
Primary	Usability - Engagement	Participants perception of the ease of use of the VR system using the User Engagement Scale (a 12 item 1-5 pt likert scale with scores between 12 and 60 and a higher score indicating greater usability)	Through study completion, 1 day
Primary	Usability - Task Demands	Participants perception of the ease of use of the VR system using the NASA Task Index (6-item scored on 10 point VAS. Items are weighted by subject perception of what is important part of task. Higher score indicates greater task demand)	Through study completion, 1 day
Primary	Usability - ease of use	Participants perception of the ease of use of the VR system using the System Usability Scale (10 item scored on 1-5 likert, scores are converted to a 100 scale with a higher score indicating greater ease of use)	Through study completion, 1 day