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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05821504
Other study ID # 2022-0465
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date August 1, 2018
Est. completion date November 21, 2018

Study information

Verified date June 2023
Source Kennesaw State University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The goal of this clinical trial was to compare to different types of high-intensity interval training in young, healthy females. The main questions were: Will changes in body composition differ between the two interventions? Will changes in endurance and muscle performance differ between the two interventions? Participants were randomized to 8 weeks of high-intensity interval training involving body weight, plyometric exercises or cycling only. Researchers compared changes in endurance performance, body composition, and muscle performance to determine if there were differences between groups.


Description:

The purpose of this study was to compare the effects of plyometric- and cycle-oriented high-intensity interval training on body composition, aerobic capacity, and skeletal muscle size, quality, and function in recreationally trained females. Young (21.7 ± 3.1 yrs), recreationally active females were randomly assigned to 8 weeks of twice weekly plyometric (n = 15) or cycling (n = 15) high-intensity interval training. The plyometric-oriented Les Mills BODYATTACK program was used for the plyometric group whereas Les Mills SPRINT, which exclusively involves stationary cycling, represented the cycling group. Both protocols involved alternating high-intensity and recovery intervals, and participants were consistently instructed to give maximal effort during the 'work' periods. The 30 min plyometric routines included four blocks of high-intensity exercise intervals. The 'work' portions consisted of the following exercises: high-knee runs, plyometric lunges, jumping jacks, squat jumps, burpees, and speed-agility patterns. The recovery periods consisted of complete rest (transitioning between exercises), a light jog, or a low impact stepping motion. On average, participants were instructed to give maximal effort for 1-2 min, with recovery intervals of 15-45 sec. Four separate routines were used throughout the duration of the study, keeping one routine per week; participants completed each routine a total of 4 times within a session. The 30 min cycling routines were performed on upright stationary bikes (Schwinn, AC Performance, Chicago, IL). Protocols involved 'work' ranging from 20-80 sec with recovery intervals between 10-60 sec. Recovery intervals consisted of complete rest on bike or particularly slow cycling. Resistance and cycling speed were relatively variable across sessions, with some intervals of higher resistance and lower speed and others involving lower resistance and higher speed (e.g., >120 RPMs). The same four workouts were used throughout the duration of the study alternating each week. Body composition (4-compartment model), VO2peak, countermovement jump performance, muscle size and echo intensity (muscle quality) as well as strength and power of the knee extensors and plantar flexors were measured before and after training. Body composition testing was completing using dual-energy x-ray absorpiometry, air displacement plethysmogrphay, and bioeletrical impedance. VO2peak was measured using a standardized maximal exercise test on a treadmill. Countermovement jump height and power was recorded with participants performing jumps on a force plate. Muscle size and quality were determined using non-invasive ultrasonography. Finally, serum growth hormone responses to the VO2peak test were measured before and after the protocols.


Recruitment information / eligibility

Status Completed
Enrollment 30
Est. completion date November 21, 2018
Est. primary completion date November 21, 2018
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 18 Years to 35 Years
Eligibility Inclusion Criteria: - Between 18-35 years of age - Female - Currently participating in 2-4 days of structured exercise for 30-75 minutes for the last 6 months Exclusion Criteria: - Currently participating in these exercise formats (2x/week within last 3 months) - Engaging in high intensity interval training for more than 30 min/week - Have diagnosed disorders/diseases in the following: cardiovascular, pulmonary, immunological, or metabolic - Current musculoskeletal injuries - Pregnant or think you may be pregnant - Currently taking any non-steroidal anti-inflammatory drug(s) or steroidal drug(s) - Currently a smoker or has consistently smoked within the last year - Has a positive written or verbal pre-study drug screen including alcohol (more than 7 drinks/week), THC/cannabinoids, amphetamines, benzodiazepines, cocaine, opioids, phencyclidine, barbiturates, cotinine. - Currently taking any medication that will significantly affect your heart rate response to exercise - If you miss four or more classes, you will be excluded from the study

Study Design


Related Conditions & MeSH terms


Intervention

Behavioral:
High-Intensity Interval Training
The training intervention is a popular exercise format that consist of alternating brief bouts of high-intensity efforts with bouts of light effort or complete rest.

Locations

Country Name City State
United States Kennesaw State University Kennesaw Georgia

Sponsors (1)

Lead Sponsor Collaborator
Kennesaw State University

Country where clinical trial is conducted

United States, 

Outcome

Type Measure Description Time frame Safety issue
Other Weekly exercising heart rate A descriptor of the exercise physiological intensity for both protocols during 8-week exercise intervention
Other Weekly exercising perceived effort Perceived intensity derived from the rating of perceived exertion scale during 8-week exercise intervention
Other Calorie consumption at baseline Amount of calories consumed at beginning and end of protocol Pre-intervention
Other Calorie consumption after 8-week intervention Amount of calories consumed at beginning and end of protocol At week 9
Other Protein consumption at baseline Amount of protein consumed at beginning and end of protocol Pre-intervention
Other Protein consumption after 8-week intervention Amount of protein consumed at beginning and end of protocol At week 9
Other Peak heart during maximal testing at baseline The highest heart rate attained during maximal exercise testing Pre-intervention
Other Peak heart during maximal testing after 8-week intervention The highest heart rate attained during maximal exercise testing At week 9
Primary Muscle composition at baseline echo-intensity value derived from ultrasound that indicates the amount of fat infiltration in muscle Pre-intervention
Primary Muscle composition after 8-week intervention echo-intensity value derived from ultrasound that indicates the amount of fat infiltration in muscle At week 9
Secondary Fat mass at baseline Amount of fat tissue a person possesses Pre-intervention
Secondary Fat mass after 8-week intervention Amount of fat tissue a person possesses At week 9
Secondary Group average growth hormone response (concentration at microLiters/Liters) at baseline The acute, exercise-induced response for growth hormone Pre-intervention
Secondary Group average growth hormone response (concentration at microLiters/Liters) after 8-week intervention The acute, exercise-induced response for growth hormone At week 9
Secondary Countermovement jump height at baseline Height of jump Pre-intervention
Secondary Countermovement jump height after 8-week intervention Height of jump At week 9
Secondary Time to peak torque at baseline How quickly muscle torque is generated Pre-intervention
Secondary Time to peak torque after 8-week intervention How quickly muscle torque is generated At week 9
Secondary Maximal oxygen consumption at baseline Standard measure of maximal oxygen consumption or peak aerobic capacity during exercise Pre-intervention
Secondary Maximal oxygen consumption after 8-week intervention Standard measure of maximal oxygen consumption or peak aerobic capacity during exercise At week 9
Secondary Body fat percentage at baseline Relative amount of body fat a person possesses Pre-intervention
Secondary Body fat percentage after 8-week intervention Relative amount of body fat a person possesses At week 9
Secondary Fat-free mass at baseline Amount of non-fat tissue a person possesses Pre-intervention
Secondary Fat-free mass after 8-week intervention Amount of non-fat tissue a person possesses At week 9
Secondary Peak torque at baseline Strength of a muscle Pre-intervention
Secondary Peak torque after 8-week intervention Strength of a muscle At week 9
Secondary Muscle cross-sectional area at baseline The size of a muscle Pre-intervention
Secondary Muscle cross-sectional area after 8-week intervention The size of a muscle At week 9
Secondary Muscle power at baseline Product of torque and velocity as determined on a dynamometer Pre-intervention
Secondary Muscle power after 8-week intervention Product of torque and velocity as determined on a dynamometer At week 9
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