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Bioavailability Study of Folate in Healthy Subjects

Healthy Clinical Trial

Official title:
A Double Blind, Randomized, Cross-over, Comparative Bioavailability Study of 3 Different Forms of Folate in Healthy Subjects

Clinical Trial Summary

The aim of this prospective interventional study is to compare the bioavailability of the 6S-5-methyltetrahydrofolate (5-MTHF) glucosamine salt versus two other forms of 5- MTHF calcium salts by measuring serum 5-MTHF responses after a single ingestion of equivalent doses of the three folate forms in humans. The hypothesis of this study is that the test products 5-MTHF glucosamine and calcium salts have equivalent bioavailabilities in serum 5-MTHF as measured by the area under the curve over a period of 24 hours (AUC0-24h) after consumption of a single dose of 5-MTHF (400μg). Participants will receive a single dose of each of the following products separated by a 7-day wash-out period: - 5-MTHF glucosamine salt - 5-MTHF calcium salt 1 - 5-MTHF calcium salt 2

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05699473
Study type Interventional
Source Lesaffre International
Contact
Status Terminated
Phase N/A
Start date January 12, 2023
Completion date May 6, 2023
View Details
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