The Efficacy of Topical Serum X for Skin Brightening

Healthy Clinical Trial

Official title:

The Efficacy of Topical Serum X Containing Arbutin and Glutathione for Skin Brightening

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05693948
• Other study ID #: UMRAMREC001-22
• Status: Completed
• Phase: N/A
• Start date: September 1, 2022
• Est. completion date: September 1, 2023

Study information

• Verified date: November 2023
• Source: Ungku Shahrin Medical Aesthetic Research & Innovation (USMARI) Centre
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study is conducted to evaluate the effectiveness of topical serum X containing arbutin and glutathione for skin brightening. The study duration is 12 weeks and the skin assessment will be carried out at baseline, week 4, 8 and week 12.The main questions this study aims to answer are: 1. The skin brightening effect of the product on facial skin. 2. To observe any adverse effect occurrence with the usage of the product.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 34
• Est. completion date: September 1, 2023
• Est. primary completion date: May 31, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• Malaysia citizen
• Male and female (age 18-30 years old)

Exclusion Criteria:

• Participant with severe acne skin condition
• Participant who is taking isotretinoin, immunocompromised patients and received laser and light treatment within the last three months
• Participant who undergo whitening or cosmetic treatments such as botox and dermal fillers within the previous six month
• Participant with a history of facial surgery such as facelift or nose reshaping
• Participant with history of allergies to any ingredient in the study product
• Participant who is pregnant or plan to get pregnant

Related Conditions & MeSH terms

• Healthy

Intervention

Other:
• Other: Serum X
Serum X contain arbutin and glutathione

Locations

Country	Name	City	State
Malaysia	Ungku Shahrin Medical Aesthetic Research & Innovation (USMARI) Centre	Petaling Jaya	Selangor

Sponsors (1)

Lead Sponsor	Collaborator
Ungku Shahrin Medical Aesthetic Research & Innovation (USMARI) Centre

Country where clinical trial is conducted

Malaysia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Changes in skin tone from baseline and at week 4, week 8, and week 12 after usage of serum X.	Skin tone will be assessed using JANUS III skin analyzer	Baseline and at week 4, week 8, and week 12
Primary	Adverse effect after using serum X	Based on adverse effect occurrence on participants that occur during study period (12 weeks	Week 12