Healthy Clinical Trial
Official title:
Assessment of Squamous Cell Carcinoma antigen2 in Verruca Vulgaris
This study aims to assess the expression of SCCA2 in the skin of patients with warts and to detect its correlation with characteristics of warts.
Status | Recruiting |
Enrollment | 50 |
Est. completion date | January 1, 2023 |
Est. primary completion date | November 1, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 1 Year and older |
Eligibility | Inclusion Criteria: - Patients present with warts (verruca vulgaris type). Exclusion Criteria: - Subjects who presenting with allergic diseases or other dermatological diseases or had a history of squamous cell carcinoma will be excluded from this study. |
Country | Name | City | State |
---|---|---|---|
Egypt | Sohag University | Sohag |
Lead Sponsor | Collaborator |
---|---|
Sohag University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Assessment of Squamous Cell Carcinoma Antigen2 in Verruca Vulgaris | Immunohistochemical staining: investigators will use monoclonal antibodies to SCCA2 (SERPINB4/ SCCA2 antibody). Immunohistochemical staining will be performed the pattern of immunostaining for SCCA2 will be evaluated in both the epidermis and dermis of wart lesions. The immunohistochemical score (IHC) range will be as follows: 0: negative expression of SCCA2; 1+: weak expression of SCCA2; 2+: moderate expression of SCCA2; and 3+: strong expression of SCCA2. | through study completion, an average of 1 year |
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