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A Study to Investigate the Effect of Single and Repeated Oral Doses of ACT-539313 on What the Body Does to Flurbiprofen, Omeprazole, Midazolam in Healthy Subjects

Healthy Clinical Trial

Official title:
A Single-center, Open-label, Four-period, Fixed-sequence Study to Investigate the Effect of Single and Repeated Oral Doses of ACT-539313 on the Pharmacokinetics of Flurbiprofen, Omeprazole, Midazolam, and Their Respective Metabolites in Healthy Subjects

Clinical Trial Summary

A study to investigate the effect of single and repeated oral doses of ACT-539313 on what the body does to flurbiprofen, omeprazole, midazolam in healthy participants.

Clinical Trial Description

A screening evaluation will be performed within 3 to 28 days (or within 10 to 28 days for women of childbearing potential) before first study treatment administration. Prior to any screening assessment, participants must sign the informed consent form. Eligibility will be based on the results of the Screening and Day -1 assessments. The participants will be confined to the study site from the morning of Day -1 until the morning of Day 2, from the morning of Day 7 until the morning of Day 9 and from the morning of Day 14 until the morning of Day 16. Participants will return to the study site for the End of Study examination on Day 17. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05254548
Study type Interventional
Source Idorsia Pharmaceuticals Ltd.
Contact
Status Completed
Phase Phase 1
Start date February 18, 2022
Completion date April 13, 2022
View Details
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