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A Single and Multiple Ascending Dose Study of Niclosamide in Healthy Volunteers

Healthy Clinical Trial

Official title:
A Randomized, Double-Blind, Single and Multiple Ascending Dose Study to Assess the Safety and Pharmacokinetics of Niclosamide in Healthy Adults

Clinical Trial Summary

A single and multiple ascending dose study of ANA001 in healthy adults to assess the safety and pharmacokinetics

Clinical Trial Description

This is a Phase 1, single center, randomized, double blind, single ascending dose (SAD) and multiple ascending dose (MAD) study to assess the safety and pharmacokinetics of ANA001 in healthy adult subjects. In the single ascending dose portion of the study, subjects in 3 cohorts of 10 subjects each will be randomized to receive a single daily oral dose of ANA001 or matching placebo. In the multiple ascending dose portion of the study, subjects in 3 cohorts of 12 subjects each will be randomized to receive twice or thrice daily oral dose of ANA001 or matching placebo. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04705415
Study type Interventional
Source NeuroBo Pharmaceuticals Inc.
Contact
Status Completed
Phase Phase 1
Start date November 17, 2020
Completion date October 28, 2022
View Details
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