Effects of Combined Interventions to Optimize Recovery During High-intensity Exercises in Healthy Adults

Healthy Clinical Trial

Official title:

Effects of Combined Interventions to Optimize Recovery During High-intensity Exercises in Healthy Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04508738
• Other study ID #: ERP_2020
• Status: Completed
• Phase: N/A
• Start date: September 10, 2020
• Est. completion date: June 30, 2021

Study information

• Verified date: October 2020
• Source: Swiss Federal Institute of Technology
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The objective of the study is to evaluate the effects a complex recovery intervention during the breaks of a repeated sprint test on exercise performance compared to placebo and control conditions. The enhanced recovery package (ERP) includes neck cooling with an iced gel pad, drinking a 6% CHO solution, mouth-rinsing with a 10% CHO, 6 mg･kg -1 caffeine solution, performing submaximal squats and hyperventilating a hyperoxic mixture; all applied in each 3-min break in-between the six 30-s sprints. This intervention will be compared to a placebo and a control condition.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 16
• Est. completion date: June 30, 2021
• Est. primary completion date: June 30, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• Informed Consent as documented by signature (Appendix Informed Consent Form)

• Healthy

• Male

• Age: 18-40 years

• Body-Mass-Index (BMI): 18.5-24.9 kg?m-2

• Trained individuals: max. Power output = 4.0 Watts?kg-1

• Non-smoking

• Willingness to adhere to the study rules

Exclusion Criteria:

• Known or suspected non-compliance, drug or alcohol abuse

• Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participants

• Previous enrolment into the current study

• Intake of medications affecting performance or the respiratory, cardiovascular or neuromuscular system

• Acute or chronic illness affecting performance or the respiratory, cardiovascular or neuromuscular system

Related Conditions & MeSH terms

• Healthy

Intervention

Other:
• ERP
The ERP intervention is applied in a randomized and counter-balanced order across visits 2-4 in each 3-min break in-between the six 30-s sprints, with one intervention per visit. The order and timing of the constituents of the interventions will be strictly constant within and between participants. ERP: 1) neck cooling with an iced gel pad, 2) drinking a ~ 6% CHO solution, 3) mouth-rinsing with a ~10% CHO, ~6 mg ? kg -1 caffeine solution, 4) performing submaximal squats and 5) hyperventilating a hyperoxic mixture
• Placebo
The control intervention is applied in a randomized and counter-balanced order across visits 2-4 in each 3-min break in-between the six 30-s sprints, with one intervention per visit. The order and timing of the constituents of the interventions will be strictly constant within and between participants. 1) neck "cooling" with room temperature gel pack, 2) drinking an artificially sweetened solution, 3) mouth-rinsing with artificially sweetened solution (containing no caffeine), 4) performing unloaded squat manoeuvres, 5) deep breaths with room air

Locations

Country	Name	City	State
Switzerland	ETH Zürich, Exercise Physiology Lab	Zürich	ZH

Sponsors (1)

Lead Sponsor	Collaborator
Swiss Federal Institute of Technology

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in mean power output	Measured over the six 30s high-intensity cycling sprints in each of the three conditions. Mean power mirrors the body's ability to generate muscle power and physical energy. Any meaningful effects of the recovery interventions will eventually translate into a higher power output.	through study completion, an expected average of 3 weeks per participant
Primary	Change in fatigue index	Fatigue index = drop in power output from the beginning to the end a 30s sprint test. The change in this index will be calculated from the 1st to the 6th sprint test in each condition.	through study completion, an expected average of 3 weeks per participant