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NCT04486248 Clinical Trial

Comparison of Magnetic Resonance Techniques for the Measurement of Cerebral Blood Perfusion

Healthy Clinical Trial

Official title:
Comparison of Magnetic Resonance Techniques for the Measurement of Cerebral Blood Perfusion

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04486248
Other study ID # ASL/BBRC2019
Secondary ID
Status Completed
Phase
First received
Last updated
Start date October 9, 2019
Est. completion date December 31, 2022

Study information
Verified date September 2021
Source Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

In this project, we aim at implementing a te-ASL sequence and to compare it to two reference ASL sequences with a fixed PLD on healthy individuals. On the one hand, the te-ASL sequence will be compared against a 3D pCASL with a PLD of 1800 ms, as the current reference according the Consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia. On the other, as the implemented te-ASL sequence will have a 2D readout, it will also be compared to a 2D pCASL ASL sequence with the same PLD, in order to be able to disentangle differences due to the dynamic PLD scheme from those arising from the different read-out schemes.

Recruitment information / eligibility
Status Completed
Enrollment 30
Est. completion date December 31, 2022
Est. primary completion date February 24, 2020
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - To sign the study informed consent form approved by the corresponding authorities. - Healthy men and women (older than 18 years old). Exclusion Criteria: - Inability or unwillingness to give written informed consent or communicate with the study staff or illiteracy. - Any contraindication to perform brain MRI procedure (e.g. pacemaker, MRI-incompatible aneurysm clips).

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Spain BarcelonaBeta Brain Research Center Barcelona

Sponsors (1)
Lead Sponsor Collaborator
Barcelonabeta Brain Research Center, Pasqual Maragall Foundation

Country where clinical trial is conducted

Spain, 

Outcome
Type Measure Description Time frame Safety issue
Primary ASL perfusion MRI data Quantification of cerebral blood flow Through study completion, an average of 1 year
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