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PK and Bioavailability Comparison of Tofacitinib Between a Modified Release and The Immediate Release Formulation

Healthy Clinical Trial

Official title:
A Phase 1, Randomized, Open-Label, 2-Way Crossover Study To Evaluate Single Dose And Steady State PK And Bioavailability Between A Modified Release Tofacitinib (11 Mg QD) And The Immediate Release Tofacitinib (5 Mg BID) In Chinese Healthy Subjects

Clinical Trial Summary

A study to characterize the single-dose and steady-state pharmacokinetics of tofacitinib Modified Release (MR) formulation as well as to compare the extent of absorption of the MR 11 mg formulation (once daily) to that of the Immediate Release (IR) 5 mg formulation (twice daily) of tofacitinib in Chinese healthy subjects under fasted conditions.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04403776
Study type Interventional
Source Pfizer
Contact
Status Completed
Phase Phase 1
Start date December 3, 2018
Completion date February 12, 2019
View Details
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