Healthy Clinical Trial
Official title:
Quantitative Assessment of the Vison Using Structural and Functional Indicators and Associations With Brain Function
Case-control studies and meta-analysis have reported that several ocular features, especially the thickness of the peripapillary retinal nerve fiber layer and visual acuity, are related to the brain degeneration and cognitive impairment. In our study, we aim to quantitatively assess ocular features using structural and functional indicators and define its associations with brain development and intelligence in children.
Status | Recruiting |
Enrollment | 200 |
Est. completion date | April 30, 2023 |
Est. primary completion date | December 30, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 3 Years to 12 Years |
Eligibility | Inclusion Criteria: - age from 3 to 12 years old Exclusion Criteria: - diagnosed with nervous system disease before |
Country | Name | City | State |
---|---|---|---|
China | Zhongshan Ophthalmic Center, Sun Yat-sen Univerisity | Guangzhou | Guangdong |
Lead Sponsor | Collaborator |
---|---|
Sun Yat-sen University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | the visual information processing function | collected with the electroencephalogram | recorded at enrollment | |
Primary | best corrected visual acuity | collected with visual acuity chart | recorded at enrollment | |
Secondary | refractive status | the refractive status of both eyes | recorded at enrollment | |
Secondary | intraocular pressure | the intraocular pressure of both eyes | recorded at enrollment | |
Secondary | fundus picture | the fundus pictures of both eyes | recorded at enrollment |
Status | Clinical Trial | Phase | |
---|---|---|---|
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