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Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT03964519
Other study ID # TMG_velocity_lost
Secondary ID
Status Not yet recruiting
Phase N/A
First received
Last updated
Start date July 1, 2019
Est. completion date September 15, 2019

Study information

Verified date May 2019
Source University of Seville
Contact Jesus Gustazo Ponce, PhD
Phone +34 658 87 41 34
Email jesusgustavo.ponce@uca.es
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study evaluates different performance, physiological and neuromuscular changes after acute and chronic resistance training intervention in physically active men. The participants will train with a single exercise (full squat) and will be monitored with a linear encoder. The experiment will consist of between 3 to 6 sets between 70% to 85% of 1RM in the full squat exercise. Two main groups will form the intervention: one group will perform inter-set repetitions until there will be a 20% of velocity loss compared to the first repetition, while the second group will have a 40% of velocity loss.


Description:

The main dependent variables and instruments will be:

1. Tensyomiography: neuromuscular properties of the vastus lateral (VL), rectus femoris (RF) and vastus medialis (VM) from the dominant leg.

2. Force platform: kinetic variables in relation to a countermovement jump.

3. Near-infrared spectrography: oxygen saturation in the VL and VM.

4. Termographic camera: low limbs temperatura.

5. Linear encoder: mean propulsive velocity from each repetition

6. Electromyography: amplitude and frequency parameters related to a knee extension maximum voluntary contraction test.

7. Strain gauge: maximum isometric force.


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 30
Est. completion date September 15, 2019
Est. primary completion date August 30, 2019
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Male
Age group 18 Years to 30 Years
Eligibility Inclusion Criteria:

- To be healthy

- Without injuries or actual illnesses

- More than 2 years of experience in resistance training or federative sports

Exclusion Criteria:

- To be sick or injured

- To have programmed during the intervention phase a dramatic change in the lifestyle

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Acute changes
In a crossover design, participants will be randomized to perform on Day 1, 3 sets of repetitions (depending on each treatment group) at 70% or 1RM in the full squat exercise. 48-h later, same will be performed but in the contrary crossover arm.
Chronic changes
In a randomized control trial, participants will train during 6 weeks the full squat exercise, 2 days in the week (minimum between-days rest of 48h). Intensity will vary from 70% to 85 of 1RM, and training volume from 3 to 6 sets.
Familiarization
Prior to any intervention, all participants will perform a familiarization of the exercise session, together with a progressive resistance test to estimate the 1 RM

Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Alejandro Muñoz López

References & Publications (15)

de Paula Simola RÁ, Harms N, Raeder C, Kellmann M, Meyer T, Pfeiffer M, Ferrauti A. Assessment of neuromuscular function after different strength training protocols using tensiomyography. J Strength Cond Res. 2015 May;29(5):1339-48. doi: 10.1519/JSC.0000000000000768. — View Citation

Franz A, Behringer M, Harmsen JF, Mayer C, Krauspe R, Zilkens C, Schumann M. Ischemic Preconditioning Blunts Muscle Damage Responses Induced by Eccentric Exercise. Med Sci Sports Exerc. 2018 Jan;50(1):109-115. doi: 10.1249/MSS.0000000000001406. — View Citation

Giovanelli N, Taboga P, Rejc E, Simunic B, Antonutto G, Lazzer S. Effects of an Uphill Marathon on Running Mechanics and Lower-Limb Muscle Fatigue. Int J Sports Physiol Perform. 2016 May;11(4):522-9. doi: 10.1123/ijspp.2014-0602. Epub 2015 Sep 21. — View Citation

González-Badillo JJ, Yañez-García JM, Mora-Custodio R, Rodríguez-Rosell D. Velocity Loss as a Variable for Monitoring Resistance Exercise. Int J Sports Med. 2017 Mar;38(3):217-225. doi: 10.1055/s-0042-120324. Epub 2017 Feb 13. — View Citation

Gutiérrez-Vargas R, Martín-Rodríguez S, Sánchez-Ureña B, Rodríguez-Montero A, Salas-Cabrera J, Gutiérrez-Vargas JC, Simunic B, Rojas-Valverde D. Biochemical and Muscle Mechanical Postmarathon Changes in Hot and Humid Conditions. J Strength Cond Res. 2018 Jul 17. doi: 10.1519/JSC.0000000000002746. [Epub ahead of print] — View Citation

Macgregor LJ, Hunter AM, Orizio C, Fairweather MM, Ditroilo M. Assessment of Skeletal Muscle Contractile Properties by Radial Displacement: The Case for Tensiomyography. Sports Med. 2018 Jul;48(7):1607-1620. doi: 10.1007/s40279-018-0912-6. — View Citation

Morán-Navarro R, Martínez-Cava A, Sánchez-Medina L, Mora-Rodríguez R, González-Badillo JJ, Pallarés JG. Movement velocity as a measure of level of effort during resistance exercise. J Strength Cond Res. 2017 Jun 2. doi: 10.1519/JSC.0000000000002017. [Epub ahead of print] — View Citation

Pareja-Blanco F, Rodríguez-Rosell D, Sánchez-Medina L, Ribas-Serna J, López-López C, Mora-Custodio R, Yáñez-García JM, González-Badillo JJ. Acute and delayed response to resistance exercise leading or not leading to muscle failure. Clin Physiol Funct Imaging. 2017 Nov;37(6):630-639. doi: 10.1111/cpf.12348. Epub 2016 Mar 11. — View Citation

Pareja-Blanco F, Rodríguez-Rosell D, Sánchez-Medina L, Sanchis-Moysi J, Dorado C, Mora-Custodio R, Yáñez-García JM, Morales-Alamo D, Pérez-Suárez I, Calbet JAL, González-Badillo JJ. Effects of velocity loss during resistance training on athletic performance, strength gains and muscle adaptations. Scand J Med Sci Sports. 2017 Jul;27(7):724-735. doi: 10.1111/sms.12678. Epub 2016 Mar 31. — View Citation

Piqueras-Sanchiz F, Martín-Rodríguez S, Martínez-Aranda LM, Lopes TR, Raya-González J, García-García Ó, Nakamura FY. Effects of moderate vs. high iso-inertial loads on power, velocity, work and hamstring contractile function after flywheel resistance exercise. PLoS One. 2019 Feb 7;14(2):e0211700. doi: 10.1371/journal.pone.0211700. eCollection 2019. Erratum in: PLoS One. 2019 Apr 12;14(4):e0215567. — View Citation

Raeder C, Wiewelhove T, Simola RÁ, Kellmann M, Meyer T, Pfeiffer M, Ferrauti A. Assessment of Fatigue and Recovery in Male and Female Athletes After 6 Days of Intensified Strength Training. J Strength Cond Res. 2016 Dec;30(12):3412-3427. — View Citation

Rodríguez-Rosell D, Yáñez-García JM, Torres-Torrelo J, Mora-Custodio R, Marques MC, González-Badillo JJ. Effort Index as a Novel Variable for Monitoring the Level of Effort During Resistance Exercises. J Strength Cond Res. 2018 Aug;32(8):2139-2153. doi: 10.1519/JSC.0000000000002629. — View Citation

Rusu LD, Cosma GG, Cernaianu SM, Marin MN, Rusu PF, Ciocanescu DP, Neferu FN. Tensiomyography method used for neuromuscular assessment of muscle training. J Neuroeng Rehabil. 2013 Jul 3;10:67. doi: 10.1186/1743-0003-10-67. — View Citation

Sánchez-Medina L, Pallarés JG, Pérez CE, Morán-Navarro R, González-Badillo JJ. Estimation of Relative Load From Bar Velocity in the Full Back Squat Exercise. Sports Med Int Open. 2017 Mar 28;1(2):E80-E88. doi: 10.1055/s-0043-102933. eCollection 2017 Feb. German. — View Citation

Wiewelhove T, Raeder C, de Paula Simola RA, Schneider C, Döweling A, Ferrauti A. Tensiomyographic Markers Are Not Sensitive for Monitoring Muscle Fatigue in Elite Youth Athletes: A Pilot Study. Front Physiol. 2017 Jun 16;8:406. doi: 10.3389/fphys.2017.00406. eCollection 2017. — View Citation

* Note: There are 15 references in allClick here to view all references

Outcome

Type Measure Description Time frame Safety issue
Primary Contraction time Time between 10% to 90% on the displacement-time curve assessed with the Tensiomiograhpy 7 weeks
Primary Maximum displacement Maximum displacement point the displacement-time curve assessed with the Tensiomiograhpy 7 weeks
Secondary Kinetic variables in the jump Kinetic variables related to the force-time curve registered with the force platform during jumps 7 weeks
Secondary Muscle tissue oxygen Oxygen in the muscle tissue assessed via near-infrared spectroscopy 7 weeks
Secondary Muscle temperature Low limb muscles temperature assessed with a termographic camera 7 weeks
Secondary Mean propulsive velocity Individual repetitions mean propulsive velocity during the full squat exercise, assessed with a linear encoder 7 weeks
Secondary Amplitude (RMS) and frequency outputs Muscle electrical activity assessed with an EMG 7 weeks
Secondary Peak isometric force Maximum force achieved during a knee extension at 120ยบ 7 weeks
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