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Pharmacokinetics of Centella Asiatica in the Elderly

Healthy Clinical Trial

Official title:
A Pharmacokinetic Study of Centella Asiatica in the Elderly

Clinical Trial Summary

This study will measure the oral bioavailability and pharmacokinetics of known bioactive compounds from a standardized Centella asiatica water extract (CAW) product (CAP) in cognitively healthy elders.

Clinical Trial Description

PRIMARY OBJECTIVES: 1. To assess the bioavailability and rate of clearance of Centella asiatica derived compounds in the plasma and urine of cognitively healthy elders over 12 hours. 2. To determine the acute tolerability of a Centella asiatica product in cognitively healthy elders. OUTLINE: Participants will orally consume a single administration of a standardized Centella asiatica water extract product (CAP). Two doses (2g and 4g CAW) will be administered on separate occasions, at least two weeks apart. The levels of known bioactive compounds present in Centella asiatica will be measured in human plasma and urine over 12 hours after administration of each of the doses. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03929250
Study type Interventional
Source Oregon Health and Science University
Contact
Status Active, not recruiting
Phase Early Phase 1
Start date July 5, 2019
Completion date December 1, 2023
View Details
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