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Dietary Nucleotides and Ribose on Muscle Fuel Utilisation — FUN  

Healthy Clinical Trial

Official title:
The Effect of Dietary Nucleotides and Ribose on Muscle Fuel Utilisation and Exercise Performance

Clinical Trial Summary

Nucleotides are the building blocks for a variety of molecules, including ATP, which is broken down in the skeletal muscle cells to provide fuel for exercise. Nucleotides can be obtained from the diet, and produced or salvaged by the body. Though nucleotides provide the building blocks for ATP, the sugar ribose has been suggested to be rate limiting for synthesising ATP.

Previous studies have shown a decrease in ATP levels in the muscle after intense exercise, and this is linked to fatigue. Other studies have also reported benefits of nucleotide and/or ribose supplementation on exercise performance. However, any potential link between ATP metabolism and exercise performance has not been explored.

This study will look at the effects of nucleotide and nucleotide-ribose supplementation in fuel utilisation and performance in skeletal muscle during endurance exercise.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03659890
Study type Interventional
Source University of Exeter
Contact
Status Completed
Phase N/A
Start date June 28, 2018
Completion date February 2, 2020
View Details
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