Healthy Clinical Trial
Official title:
Effect of Changes in Glucose Intake and Sweet Perception on Post Prandial Glycaemia
Sugar-sweetened beverages are the main source of added sugars in most Westernized countries,
and for this reason constitute a primary target for sugar reduction by many companies,
including Nestlé. Instead of using high-intensity sweeteners which are non-caloric in nature,
an alternative would be to reduce sugars without altering sweetness.
In this protocol, the general goal is to investigate the relative contribution of sweet taste
perception and sugar intake on post-prandial glucose response. 4 different nutritional
products will be tested by 16 healthy subjects in a crossover design.
After enrollment, participants will be asked to come to the investigational site 6 times for:
- two sensory tests dedicated to assess the sensory capacity of the participants from the
same sensory test repeated twice, for better consistency.
- 4 testing visits for a 3-h blood kinetics after each product intake. These visits will
be scheduled on different days separated by a washout period of at least one week.
Outcomes will be glycemia and insulinemia.
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