Sleep Inertia and Functional Connectivity

Healthy Clinical Trial

Official title:

Sleep Inertia and Functional Connectivity Between Brain Regions at Awakening : a Functional Magnetic Resonance Imaging (fMRI) Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03058159
• Other study ID #: 69HCL16_0675
• Status: Completed
• Phase: N/A
• Start date: March 5, 2015
• Est. completion date: July 3, 2017

Study information

• Verified date: June 2018
• Source: Hospices Civils de Lyon
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of the study is to investigate the functional connectivity between the brain regions of the default mode network before and after a 40 min nap slot in the afternoon. The hypothesis is that connectivity between brain regions will be decreased after the nap as compared to before the nap.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 55
• Est. completion date: July 3, 2017
• Est. primary completion date: May 24, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• 65 > age > 18

• high or law dream recall frequency

Exclusion Criteria:

• history of psychiatric or neurologic or sleep pathologies

• counter indication for MRI

Related Conditions & MeSH terms

• Healthy

Intervention

Other:
• fMRI
fMRI scans will be acquired before and after a 40 min nap slot in the afternoon. Functional connectivity between brain region will be assessed analyzing the scans with the CONN toolbox of the Statistical Parametric Mapping (SPM) software.

Locations

Country	Name	City	State
France	CH le VINATIER	Bron

Sponsors (1)

Lead Sponsor	Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Measure: Change of correlation values between the BOLD (Blood Oxygenation Level Dependent) signal time series of the brain regions of the default mode network (DMN) between the scans before and after the nap slot.	The hypothesis is that connectivity between the brain regions of the default mode network will be decreased after the nap as compared to before the nap and that it will be more the case for subjects with a high dream recall frequency as compared to subjects with a law dream recall frequency. fMRI scans will be acquired before and after a 40 min nap slot in the afternoon. Functional connectivity between brain region will be assessed analyzing the scans with the functional connectivity toolbox (CONN) of the Statistical Parametric Mapping (SPM) software.	fMRI scans will be acquired 5 min before, 5 min after and 25min after the nap slot.