The Effect of Protein Ingestion on the Recovery of Skeletal Muscle Function Following Eccentric Exercise.

Healthy Clinical Trial

— SPADE  

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02980900
• Other study ID #: 181739
• Status: Completed
• Phase: N/A
• Start date: January 1, 2017
• Est. completion date: August 1, 2018

Study information

• Verified date: October 2018
• Source: University of Exeter
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The present study will assess the effect of the type and timing of protein ingestion 6 days prior to, and 7 days following eccentric exercise on the time course of 1) the recovery of muscle function, 2) the recovery of perceived muscle soreness, 3) muscle metabolism.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 36
• Est. completion date: August 1, 2018
• Est. primary completion date: August 1, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Men and women who are generally healthy and recreationally active

Exclusion Criteria:

• Active cardiovascular disease or hypertension

• Diagnosed metabolic impairment

• Use of nutritional supplements

• Use of anti-inflammatory medications

• Habitual dietary protein intake of <0.8g/kg/day

• Musculoskeletal disorders

Related Conditions & MeSH terms

• Healthy

Intervention

Dietary Supplement:
• Post exercise protein-polyphenol supplement
Participants will ingest a post exercise protein-polyphenol supplement. This will begin 6 days before eccentric exercise and will end 6 days after eccentric exercise.
• Post exercise placebo supplement
Participants will ingest an isocaloric placebo supplement after exercise. This will begin 6 days before eccentric exercise and will end 6 days after eccentric exercise.
• Pre bed protein-polyphenol supplement
Participants will ingest a protein-polyphenol supplement before bed. This will begin 6 days before eccentric exercise and will end 6 days after eccentric exercise.
• Pre bed placebo supplement
Participants will ingest an isocaloric placebo supplement before bed. This will begin 6 days before eccentric exercise and will end 6 days after eccentric exercise.

Locations

Country	Name	City	State
United Kingdom	Sport and Health Sciences	Exeter	Devon

Sponsors (1)

Lead Sponsor	Collaborator
University of Exeter

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Isokinetic force production of the knee extensor muscles		14 days
Secondary	Muscle protein synthesis		14 days
Secondary	Thigh volume		14 days
Secondary	Perceived muscle soreness		14 days
Secondary	Isometric force production of the knee extensor muscles		14 days