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Influence of Triflusal on Cognitive Functions in Subjects Under Chronic Stress — Tricross-Basel  

Healthy Clinical Trial

Official title:
Randomized Placebo Controlled Phase II Cross Over Study on the Influence of Triflusal on Cognitive Functions in Subjects Under Chronic Stress

Clinical Trial Summary

The purpose of this study is to investigate the effects of the eNOS activating agent triflusal on episodic memory and cognitive functions in participants under chronic stress.

Clinical Trial Description

Randomised, placebo controlled, double blind, cross-over design

Primary study outcome is:

Performance in a verbal memory task.

Main secondary outcomes are: Performance in working memory and cognitive tasks and influence on mood, depression and anxiety and subjective memory impairment.

Once daily oral administration of 600 mg triflusal and placebo mannitol for 8 days in a cross-over trial with a washout period of at least 14 days between the two periods. Each participant will take triflusal as well as placebo ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02904109
Study type Interventional
Source University of Basel
Contact
Status Completed
Phase Phase 2
Start date September 13, 2016
Completion date February 28, 2017
View Details
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