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Sucralose Effects on Glucose Metabolism and Gut Microbiota

Healthy Clinical Trial

Official title:
Effects of Sucralose Consumption on Glucose Metabolism, Incretin and Gut Microbiota in Healthy Adult

Clinical Trial Summary

Hypothesis:

1. Long-term consumption of sucralose may effect glucose metabolism, incretin hormone secretion and gut microbiota in healthy adults.

2. Long-term consumption of sucralose may alter food behaviour in healthy adults.

Clinical Trial Description

Artificial sweeteners such as sucralose, are among the most widely used food additives worldwide. Artificial sweetener consumption is considered safe and beneficial owing to their low caloric content. However, many emerging evidences showed artificial sweeteners may induce glucose intolerance. The objectives of this study were to determine the effect of sucralose on glycemic response, insulin secretion, insulin sensitivity, incretin response, gut microbiota and food behavior in healthy subjects. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02650947
Study type Interventional
Source Ramathibodi Hospital
Contact
Status Completed
Phase N/A
Start date January 2016
Completion date April 2017
View Details
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