Subfoveal Choroidal Thickness in Thai Population

Healthy Clinical Trial

Official title:

Subfoveal Choroidal Thickness in Thai Population

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT02551601
• Other study ID #: HE561056
• Status: Terminated
• Start date: August 2015
• Est. completion date: August 2018

Study information

• Verified date: August 2019
• Source: Khon Kaen University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this study was to determine the subfoveal choroidal thickness in normal Thai eyes and study the associations with gender, age, refractive error and axial length using spectral-domain optical coherence tomography with enhanced depth imaging technique.

Description:

Alteration of choroidal blood supply causes changes in choroidal thickness and results in choroidal abnormalities. These are usually associated with retinal diseases and leading to severe visual dysfunction. Choroidal thickness is therefore helpful in diagnosis and treatment for many chorioretinal conditions. With the advent of spectral domain optical coherence tomography and enhanced depth imaging technique, choroidal thickness has been investigated widely in normal eyes and various chorioretinal diseases including central serous chorioretinopathy (CSC), age-related macular degeneration (AMD), highly myopia and Vogt Koyanagi-Harada disease. Similar to retinal thickness, a normal baseline choroidal thickness might be used for interpretation. This value might be affected by several variables including age, gender and ethnicity. Although there were previous studies on subfoveal choroidal thickness in normal eyes from many countries, there has been no such study in Thailand. The purpose of this study was to determine the subfoveal choroidal thickness in normal Thai eyes and study the associations with gender, age, refractive error and axial length using SD-OCT and EDI technique.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 150
• Est. completion date: August 2018
• Est. primary completion date: August 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age 18 years or above

• Healthy subjects

• No ocular diseases

• Written informed consent form

Exclusion Criteria:

• patients with systemic diseases that may affect retinal or choroidal thickness including diabetes

• patients with history of refractive surgeries, intraocular surgeries or retinal laser treatments

• patients with history of macular, retinal, or optic nerve abnormalities

Related Conditions & MeSH terms

• Healthy

Intervention

Other:
• measure subfoveal choroidal thickness
measure subfoveal choroidal thickness using optical coherence tomography

Locations

Country	Name	City	State
Thailand	Eye outpatients department, Srinagarind Hospital, Khon Kaen University	Khon Kaen

Sponsors (1)

Lead Sponsor	Collaborator
Khon Kaen University

Country where clinical trial is conducted

Thailand, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	subfoveal choroidal thickness	Thickness of choroid at the foveal area	up to 4 months