Effect of Low-level Laser Therapy (808nm) on Marker of Muscle Damage

Healthy Clinical Trial

Official title:

Effect of Low-level Laser Therapy (808nm) on Marker of Muscle Damage: Randomized Double-blind Placebo-controlled Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01808716
• Other study ID #: CEP/UFRN 176/10
• Status: Completed
• Phase: N/A
• First received: March 1, 2013
• Last updated: March 7, 2013
• Start date: February 2011
• Est. completion date: June 2012

Study information

• Verified date: March 2013
• Source: Universidade Federal de Sao Carlos
• Contact: n/a
• Is FDA regulated: No
• Health authority: Brazil: National Committee of Ethics in Research
• Study type: Interventional

Clinical Trial Summary

The study hypothesis is a decreased muscle damage induced by exercises when low-level laser therapy is applied on body muscles before exercises.

Description:

The study assessed males submitted to exercise to induce muscle damage. Creatine kinase levels in blood was quantified in order to identify the magnitude of muscle damage.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 22
• Est. completion date: June 2012
• Est. primary completion date: October 2011
• Accepts healthy volunteers: No
• Gender: Male
• Age group: 25 Years to 35 Years

Eligibility

Inclusion Criteria:

• healthy males,

• physically active,

• aged between 25-40 years.

Exclusion Criteria:

• smoker, or

• under medicine as anti-inflammatory and/or any drug that could affect normal and physiological conditions and lesion in upper limbs.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Healthy

Intervention

Device:
• Low-level laser therapy (808nm) and exercise
Use of low-level laser therapy(LLLT)or placebo-LLLT applied on biceps brachii for muscle damage recovery

Locations

Country	Name	City	State
Brazil	Federal Univesity of Rio Grande do Norte	Natal	Rio Grande do Norte

Sponsors (2)

Lead Sponsor	Collaborator
Universidade Federal de Sao Carlos	Universidade Federal do Rio Grande do Norte

Country where clinical trial is conducted

Brazil, 

References & Publications (2)

Ferraresi C, de Brito Oliveira T, de Oliveira Zafalon L, de Menezes Reiff RB, Baldissera V, de Andrade Perez SE, Matheucci Júnior E, Parizotto NA. Effects of low level laser therapy (808 nm) on physical strength training in humans. Lasers Med Sci. 2011 May;26(3):349-58. doi: 10.1007/s10103-010-0855-0. Epub 2010 Nov 18. — View Citation

Vieira WH, Ferraresi C, Perez SE, Baldissera V, Parizotto NA. Effects of low-level laser therapy (808 nm) on isokinetic muscle performance of young women submitted to endurance training: a randomized controlled clinical trial. Lasers Med Sci. 2012 Mar;27(2):497-504. doi: 10.1007/s10103-011-0984-0. Epub 2011 Aug 26. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Creatine Kinase analysis in blood	Evaluation of Creatine Kinase (CK) levels in blood before, immediately after and 24h, 48h and 72h after protocol of exercise to induce muscle damage	72 hours	No

External Links

•   Research Ethics Committee of the Federal University of Rio Grande do Norte