Effects of Low Level Laser Therapy (808nm) on Muscle Performance of Young Women Submitted to Physical Training

Healthy Clinical Trial

Official title:

Effects of Low Level Laser Therapy (808nm) on Muscle Performance of Young Women Submitted to Physical Training

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01391195
• Other study ID #: CAAE - 0100.0.135.000-05
• Status: Completed
• Phase: Phase 1
• First received: July 7, 2011
• Last updated: July 12, 2011
• Start date: January 2006
• Est. completion date: October 2007

Study information

• Verified date: December 2005
• Source: Universidade Federal de Sao Carlos
• Contact: n/a
• Is FDA regulated: No
• Health authority: Brazil: National Committee of Ethics in Research
• Study type: Interventional

Clinical Trial Summary

The study hypothesis is an increase in muscle performance and a higher aerobic adaptation of young women submitted to chronic endurance training program associated to low level laser therapy when compared to chronic aerobic training alone.

Description:

The study assessed women muscle performance in isokinetic dynamometry, ventilatory parameters such as ventilatory threshold, VO2Peak, VO2Max, Ventilation. Maximal load in cycle ergometer test (Balke's protocol), Borg Scale and Heart rate were assessed too.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 45
• Est. completion date: October 2007
• Est. primary completion date: April 2007
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 28 Years

Eligibility

Inclusion Criteria:

• healthy young women volunteers

• women with a beginner or moderately trained pattern of physical activity

• body Mass Index (BMI) between 18 and 25kg/m2

Exclusion Criteria:

• previous injury to the femoral quadriceps or hamstrings muscles (within 6 months prior to study)

• osseous or articular disorder in the lower limbs

• cardiovascular system disorders or systemic disease

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Healthy

Intervention

Device:
• Phototherapy by low level laser therapy
Phototherapy by low level laser therapy during 9 weeks

Locations

Country	Name	City	State
Brazil	Universidade Federal de Sao Carlos	São Carlos	São Paulo

Sponsors (2)

Lead Sponsor	Collaborator
Universidade Federal de Sao Carlos	Conselho Nacional de Desenvolvimento Científico e Tecnológico

Country where clinical trial is conducted

Brazil, 

References & Publications (8)

Baroni BM, Leal Junior EC, De Marchi T, Lopes AL, Salvador M, Vaz MA. Low level laser therapy before eccentric exercise reduces muscle damage markers in humans. Eur J Appl Physiol. 2010 Nov;110(4):789-96. doi: 10.1007/s00421-010-1562-z. Epub 2010 Jul 3. — View Citation

Baroni BM, Leal Junior EC, Geremia JM, Diefenthaeler F, Vaz MA. Effect of light-emitting diodes therapy (LEDT) on knee extensor muscle fatigue. Photomed Laser Surg. 2010 Oct;28(5):653-8. doi: 10.1089/pho.2009.2688. Epub 2010 Jul 13. — View Citation

Ferraresi C, de Brito Oliveira T, de Oliveira Zafalon L, de Menezes Reiff RB, Baldissera V, de Andrade Perez SE, Matheucci Júnior E, Parizotto NA. Effects of low level laser therapy (808 nm) on physical strength training in humans. Lasers Med Sci. 2011 May;26(3):349-58. doi: 10.1007/s10103-010-0855-0. Epub 2010 Nov 18. — View Citation

Leal Junior EC, Lopes-Martins RA, Baroni BM, De Marchi T, Taufer D, Manfro DS, Rech M, Danna V, Grosselli D, Generosi RA, Marcos RL, Ramos L, Bjordal JM. Effect of 830 nm low-level laser therapy applied before high-intensity exercises on skeletal muscle recovery in athletes. Lasers Med Sci. 2009 Nov;24(6):857-63. doi: 10.1007/s10103-008-0633-4. Epub 2008 Dec 5. — View Citation

Leal Junior EC, Lopes-Martins RA, Dalan F, Ferrari M, Sbabo FM, Generosi RA, Baroni BM, Penna SC, Iversen VV, Bjordal JM. Effect of 655-nm low-level laser therapy on exercise-induced skeletal muscle fatigue in humans. Photomed Laser Surg. 2008 Oct;26(5):419-24. doi: 10.1089/pho.2007.2160. — View Citation

Leal Junior EC, Lopes-Martins RA, de Almeida P, Ramos L, Iversen VV, Bjordal JM. Effect of low-level laser therapy (GaAs 904 nm) in skeletal muscle fatigue and biochemical markers of muscle damage in rats. Eur J Appl Physiol. 2010 Apr;108(6):1083-8. doi: 10.1007/s00421-009-1321-1. Epub 2009 Dec 19. — View Citation

Leal Junior EC, Lopes-Martins RA, Vanin AA, Baroni BM, Grosselli D, De Marchi T, Iversen VV, Bjordal JM. Effect of 830 nm low-level laser therapy in exercise-induced skeletal muscle fatigue in humans. Lasers Med Sci. 2009 May;24(3):425-31. doi: 10.1007/s10103-008-0592-9. Epub 2008 Jul 23. — View Citation

Lopes-Martins RA, Marcos RL, Leonardo PS, Prianti AC Jr, Muscará MN, Aimbire F, Frigo L, Iversen VV, Bjordal JM. Effect of low-level laser (Ga-Al-As 655 nm) on skeletal muscle fatigue induced by electrical stimulation in rats. J Appl Physiol (1985). 2006 Jul;101(1):283-8. Epub 2006 Apr 20. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Fatigue Index of knee extensor muscles	Fatigue Index of knee extensor muscles assessed in isokinetic dynamometry.	nine weeks	No
Primary	Ventilatory threshold	Ventilatory threshold quantified by a gas analyzer.	nine weeks	No
Primary	VO2max	VO2max quantified by a gas analyzer.	nine weeks	No
Primary	VO2peak	VO2peak quantified by a gas analyzer.	nine weeks	No
Primary	Maximum load of effort on cycle ergometer (Balke's protocol).	Maximum load of effort on cycle ergometer quantified in Watts.	nine weeks	No
Secondary	Total work of knee extensor muscles	Total work of knee extensor muscles assessed in isokinetic dynamometry	nine weeks	No
Secondary	Peak torque of knee extensor muscles	Peak torque of knee extensor muscles assessed in isokinetic dynamometry	nine weeks	No
Secondary	Borg scale	Subjective effort perception assessed by Borg scale	nine weeks	No
Secondary	Heart rate	Heart Rate assessed by cardiac frequency meter	nine weeks	No

External Links

•   Ethics in Human Research Committee of the Federal University of São Carlos
•   Federal University of São Carlos