Healthy Clinical Trial
Official title:
Central Blood Pressure Follow-up Study in Japanese
Purpose of the study
1. The predictive value of central aortic pressure and aortic pulse wave velocity (PWV) in
a Japanese population is not known. The purpose of this study is to quantify the
predictive value of these indices in the determination of cardiovascular risk.
2. Recently, a non-invasive method to separate the aortic pressure waveform into the
separate ejection pressure wave and reflected pressure wave has become available. With
this decomposition method, it is possible to estimate aortic PWV (named AVI). The
second objective of this study is to determine if AVI can be a substitute for
carotid-femoral PWV (cf-PWV), the current gold standard for aortic PWV measurement.
3. To study vascular aging of the Japanese population by evaluating central blood pressure
and aortic PWV by age, and compare these values to similar studies done in Caucasian
and Chinese patient populations.
4. To study the relationship between the magnitude of the aortic reflected pressure wave
and the degree of left ventricular (LV) hypertrophy and LV diastolic function.
n/a
Observational Model: Cohort, Time Perspective: Prospective
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