Local Effects of Epinephrine on Lactate, Glucose, Lipid and Protein Metabolism in Bilaterally Perfused Human Legs

Healthy Clinical Trial

Official title:

Local Effects of Epinephrine on Lactate, Glucose, Lipid and Protein Metabolism in Bilaterally Perfused Human Legs

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01116609
• Other study ID #: Epi-perfusion
• Status: Completed
• Phase: N/A
• First received: April 9, 2010
• Last updated: November 4, 2011
• Start date: October 2004
• Est. completion date: January 2010

Study information

• Verified date: November 2011
• Source: University of Aarhus
• Contact: n/a
• Is FDA regulated: No
• Health authority: Denmark: The Regional Committee on Biomedical Research Ethics
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to define the local metabolic effects of epinephrine in the bilaterally perfused human leg.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 10
• Est. completion date: January 2010
• Est. primary completion date: November 2009
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• Male

Exclusion Criteria:

• Comorbidity

• Females

Study Design

Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Single Blind (Subject), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Healthy

Intervention

Drug:
• Epinephrine
unilateral leg infusion of Epinephrine 0.4 micrograms/m2/min

Locations

Country	Name	City	State
Denmark	Medical research laboratories, Aarhus University Hospital	Aarhus

Sponsors (1)

Lead Sponsor	Collaborator
University of Aarhus

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Arterio-Venous balances of metabolites	Acute regional effect of epinephrine infusion in the femoral artery	6 hours infusion	No