Healthy Clinical Trial
Official title:
Reproducibility of Retinal Thickness and Volume Measurements Determined With the Cirrus Spectral Domain OCT
| NCT number | NCT00643422 |
| Other study ID # | Cirrus_OCT_0308 |
| Secondary ID | |
| Status | Completed |
| Phase | N/A |
| First received | March 22, 2008 |
| Last updated | July 21, 2008 |
In this study the reproducibility of optical coherence tomography measurements should be evaluated.
| Status | Completed |
| Enrollment | 16 |
| Est. completion date | |
| Est. primary completion date | |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | Both |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - 18 years of age or older - best corrected visual acuity of at least 20/25 - clear optical media Exclusion Criteria: - any kind of retinal pathology - any kind of opacity of optical media - any kind of intraocular surgery - spherical refraction of more than 5 diopters - cylindrical refraction of more than 3 diopters - amblyopia |
Observational Model: Cohort, Time Perspective: Prospective
| Country | Name | City | State |
|---|---|---|---|
| Austria | Rudolf Foundation Clinic | Vienna |
| Lead Sponsor | Collaborator |
|---|---|
| The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery |
Austria,
Budenz DL, Fredette MJ, Feuer WJ, Anderson DR. Reproducibility of peripapillary retinal nerve fiber thickness measurements with stratus OCT in glaucomatous eyes. Ophthalmology. 2008 Apr;115(4):661-666.e4. Epub 2007 Aug 13. — View Citation
Danis RP, Fisher MR, Lambert E, Goulding A, Wu D, Lee LY. Results and repeatability of retinal thickness measurements from certification submissions. Arch Ophthalmol. 2008 Jan;126(1):45-50. doi: 10.1001/archopht.126.1.45. — View Citation
Diabetic Retinopathy Clinical Research Network, Krzystolik MG, Strauber SF, Aiello LP, Beck RW, Berger BB, Bressler NM, Browning DJ, Chambers RB, Danis RP, Davis MD, Glassman AR, Gonzalez VH, Greenberg PB, Gross JG, Kim JE, Kollman C. Reproducibility of macular thickness and volume using Zeiss optical coherence tomography in patients with diabetic macular edema. Ophthalmology. 2007 Aug;114(8):1520-5. Epub 2007 Mar 13. — View Citation
Hsu SY, Tsai RK. Analysis of retinal nerve fiber layer and macular thickness measurements in healthy Taiwanese individuals using optical coherence tomography (Stratus OCT). J Glaucoma. 2008 Jan-Feb;17(1):30-5. doi: 10.1097/IJG.0b013e31811243b4. — View Citation
Paunescu LA, Schuman JS, Price LL, Stark PC, Beaton S, Ishikawa H, Wollstein G, Fujimoto JG. Reproducibility of nerve fiber thickness, macular thickness, and optic nerve head measurements using StratusOCT. Invest Ophthalmol Vis Sci. 2004 Jun;45(6):1716-24. — View Citation
Polito A, Del Borrello M, Isola M, Zemella N, Bandello F. Repeatability and reproducibility of fast macular thickness mapping with stratus optical coherence tomography. Arch Ophthalmol. 2005 Oct;123(10):1330-7. — View Citation
Sadda SR, Tan O, Walsh AC, Schuman JS, Varma R, Huang D. Automated detection of clinically significant macular edema by grid scanning optical coherence tomography. Ophthalmology. 2006 Jul;113(7):1187.e1-12. Epub 2006 May 2. — View Citation
Wang XY, Huynh SC, Burlutsky G, Ip J, Stapleton F, Mitchell P. Reproducibility of and effect of magnification on optical coherence tomography measurements in children. Am J Ophthalmol. 2007 Mar;143(3):484-8. Epub 2006 Dec 22. — View Citation
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | retinal thickness | two | No | |
| Secondary | retinal volume | two | No |
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