Healthy Clinical Trial - Determinants of Warfarin Metabolism

Status Recruiting

Clinical Trial Summary

The anticoagulant effect of warfarin varies greatly among individuals. Some of this variability is attributed to differences in the activity of CYP2C9, the predominant enzyme involved in the metabolism of S-warfarin.

The present study is designed to define the differences in warfarin metabolism among healthy individuals carrying different CYP2C9 genotypes. In addition, the study will define the correlation between the phenytoin metabolic ratio, a marker of CYP2C9 activity in vivo, and warfarin metabolism.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Healthy

Clinical Trial Details

NCT number	NCT00162474
Study type	Interventional
Source	Hadassah Medical Organization
Contact	Yoseph Caraco, MD
Phone	00 972 2 6778584
Email	caraco@hadassah.org.il
Status	Recruiting
Phase	N/A
Start date	September 2003
Completion date	December 2020

View Details

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