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Healthy Young Adults clinical trials

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NCT ID: NCT06043076 Completed - Clinical trials for Healthy Young Adults

iTBS Effect on M1 Plasticity, Blood Glucose, and Cardiovascular Response

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

Transcranial magnetic stimulation is a medical device that can alter motor cortical (M1) excitability through the scalp via various protocols. Among these, intermittent theta-burst stimulation (iTBS) is a novel protocol that enhances the M1 excitability for several minutes beyond stimulation. The changes in M1 excitability might in turn be accompanied by other physiological responses in the human body. This study will explore the effect of iTBS protocol on M1 plasticity, heart rate, blood pressure, and blood glucose in healthy young adults in comparison to sham stimulation.

NCT ID: NCT05876663 Completed - Clinical trials for Healthy Young Adults

Effect of Kinesio Taping on Pulmonary Function and Forward Shoulder Posture FSP of Young Adults

FSP
Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the effect of kinesio taping on pulmonary function and forward shoulder posture in young adults. Limited literature shows an association between forward shoulder posture and pulmonary function but the effect of kinesio taping for correction of forward shoulder posture and its consequences on pulmonary function is lacking in previous studies.

NCT ID: NCT05515926 Completed - Clinical trials for Healthy Young Adults

Physiological Responses to Osteopathic Manipulative Techniques in Healthy Young Adults

Start date: October 4, 2013
Phase: N/A
Study type: Interventional

This study was designed to investigate the effect of selected osteopathic manipulative techniques (OMT) on cardiovascular functions in healthy young men and women. This work addressed questions regarding physiological responses to OMT in maintaining the cardiovascular homeostasis by (1) measuring changes in the cardiac autonomic nerves activity, (2) measuring changes in cardiovascular parameters such as blood pressure, cardiac contractility, and heart rate, and (3) investigating if changes in the cardiac autonomic nerves activity were related to changes in blood pressure, cardiac contractility, or heart rate. This controlled not-randomized pilot study with repeated measures was conducted at the Touro University Nevada College of Osteopathic Medicine. Healthy 21-35 years old students and employees volunteered in the study. The experimental group received the three cranial osteopathic manipulative techniques, occipital-atlantal decompression, occipital-mastoid decompression, and compression of the fourth ventricle, consecutively applied. This study included two control groups; one group received sham manipulations, and the second group did not receive any manipulations and was the non-touch group. The computerized MP150 BIOPAC System was used for data collection and analysis. The skin electrodes were used for the one-lead ECG and impedance cardiography. Digital data were recorded during the entire experimental protocol. The blood pressure was measured manually before and after the experimental procedure using blood pressure cuff and stethoscope. Cardiovascular responses to OMT were evaluated by using the heart rate variability test (HRV), calculating changes in cardiac contractility, and comparing changes in pre- and post- blood pressure readings. An analysis of variance (ANOVA) with a Bonferroni post-hoc test was used to evaluate treatment effects. The type I error rate (alpha) was set at 0.05.

NCT ID: NCT05407259 Not yet recruiting - Clinical trials for Healthy Young Adults

Investigating the Inverted-U Relationship Between Cognitive Performance and Plasma Epinephrine

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

Abstract Although acute resistance exercise has been suggested to enhance inhibitory control, a critical component of executive function, the mechanism by which acute exercise influences inhibitory control is unclear and there are methodological limitations in previous empirical studies. According to the locus coeruleus-norepinephrine (LC-NE) theory, the activity of the LC, the major releaser of NE in the brain, regulates inhibitory control. Because there is reciprocal communication between circulating epinephrine and the LC. Plasma epinephrine is chosen as the index of LC-NE activity. However, only one study in acute exercise-inhibitory control measured the plasma epinephrine. Therefore, this registered report aims to extend its findings by a four-arm crossover randomized controlled design with three different intensities, using free-weight, multiple-joint, and structural resistance exercises. Moreover, most studies showed some methodological limitations such as failing to report the process of randomization, implementing a familiarization of resistance exercise before the maximal strength test, and publishing the protocol. Without a transparent report on how the participants were allocated, the results were at risk of bias. Without a familiarization of resistance exercise, the maximal muscle strength was likely to be underestimated. Without publishing the protocol before data collection, these findings were threatened by undetected researchers' degrees of freedom such as HARKing (hypothesizing after the results are known), cherry picking, and p-hacking. This registered report will address the limitations of previous studies by incorporating cognitive and resistance exercise familiarization, transparently reporting the randomization process, and submitting it as a registered report.

NCT ID: NCT04391777 Not yet recruiting - Clinical trials for Healthy Young Adults

Determine the Effect of the Fourth Ventricle Compression Technique on Physiological Variables

Start date: September 2024
Phase: N/A
Study type: Interventional

This study aims to analyze the influence of the fourth ventricle compression technique in heart rate, respiratory rate, blood pressure, conductivity and thermal variability of the skin in healthy young adults.

NCT ID: NCT04302155 Completed - Clinical trials for Healthy Young Adults

Wii Fit as Balance Assessment and Training

Start date: August 15, 2018
Phase: N/A
Study type: Interventional

Balance play a vital role to increase motor skills in healthy young adults. With increasing age balance control ability decreases,this decline can result as early as mid-30s. In young adults focus on improving anticipatory postural control so risk of lower extremity injuries especially ankle and knee injuries can be minimized and future risk of fall can be minimized.Objective is To compare the effect of traditional versus Wii fit training on balance in young adults the participants were randomly assigned into two groups interventional and control. total 18 minutes session was given to both groups wii fit group and traditional balance training group. all participants were given 3 sessions per week for 6. participants were initially accessed initially for eligibility , these participants were randomly divided into wii fit and traditional training group through sealed enveloped method . the initial assessment was done on wii fit. balance intervention to wii fit group is different games available on wii fit software. balance intervention given to traditional group is on trampoline and on BOSU ball.

NCT ID: NCT04207528 Completed - Clinical trials for Healthy Young Adults

Campus Life Study: Harnessing Generativity Among Young Adults

Start date: January 6, 2020
Phase: N/A
Study type: Interventional

Recent research suggests that short, online interventions can enhance well-being, which is beneficial to both physical and mental health outcomes. Further, growing evidence suggests that prosocial behavior—a behavior that can be reliably manipulated through a short online intervention—may have beneficial effects on well-being and physical health. Giving support to others appears to be just as beneficial as receiving support, and asking people to perform kind acts for others over the course of several weeks, for example, has been shown to both increase well-being and reduce the inflammatory potential of immune cells. The purpose of the current study is to test a novel 3-week, online prosocial writing-based intervention in a sample of young adults. Previous intervention studies have manipulated prosocial behavior by asking participants to perform tangible acts of kindness for others, such as writing a note to a coworker or helping a neighbor. However, providing this type of direct support can be logistically challenging and may contribute to increased feelings of distress in certain contexts. Writing interventions designed to elicit feelings of generativity offer one alternative approach, though they have yet to be tested among young adults. Participants (n = 200) will be randomized to one of two conditions--peer helping or a facts-only control--and instructed to write about their experiences in their first-year at UCLA (freshman or first-year after transfer). Those in the peer helping will be asked to write for the benefit of a student who is about to begin their first year, whereas those in the facts-only control will not. In total, participants will complete 4 writing assignments, each on a separate day over the course of one week. Valid self-report measures will be assessed at pre-intervention, each writing session, post-intervention, and at the 2-week follow-up. The investigators expect participants in the peer helping condition to experience a greater increase in well-being (primary outcome) across the intervention and the follow-up when compared to the control condition. Secondary outcomes will include depressive symptoms, anxiety, loneliness, physical symptoms, social support, and generativity. As an exploratory aim, will also assess several moderators (i.e., psychological distress, prosocial tendencies, generativity) and mediators (i.e., fulfillment of psychological needs, positive affect) of the intervention effects.

NCT ID: NCT03628976 Completed - Clinical trials for Healthy Young Adults

Noninvasive Vagus Nerve Stimulation (VNS) for Neuromotor Adaptations

Start date: May 20, 2019
Phase: N/A
Study type: Interventional

The study will examine how electrical stimulation of vagus nerve (i.e. nerve around the outer ear) from the skin surface during motor training influences a brain hormone (called norepinephrine), brain activity, and motor performance.

NCT ID: NCT03512041 Completed - Clinical trials for Healthy, Young Adults

Effect of Number of Remote Limb Ischemic Conditioning Cycles on Learning Enhancement

RLICC
Start date: December 13, 2016
Phase: Phase 1
Study type: Interventional

The purpose of this research study is to determine the effect of number of remote limb ischemic conditioning (RLIC) cycles on enhancing learning in neurologically intact young adults.

NCT ID: NCT03512028 Completed - Clinical trials for Healthy, Young Adults

Remote Limb Ischemic Conditioning to Enhance Learning and Muscle Strength in Healthy Young Adults

Start date: November 8, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this research study is to determine if remote limb ischemic conditioning (RLIC) can enhance learning of a motor (balance) and an ecologically valid, complex cognitive-motor (driving) task, and increase skeletal muscle strength in neurologically-intact young adults.