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Healthy Volunteers clinical trials

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NCT ID: NCT01711762 Completed - Healthy Volunteer Clinical Trials

A Pharmacokinetics Study of Radioactive-Labeled GDC-0973 in Healthy Male Volunteers

Start date: September 2012
Phase: Phase 1
Study type: Interventional

This open-label, non-randomized study will assess the absorption, metabolism, and excretion of radioactive-labeled [14C]-GDC-0973 in healthy male volunteers. Volunteers will receive a single dose of [14C]-GDC-0973.

NCT ID: NCT01710670 Completed - Healthy Volunteers Clinical Trials

A Study to Investigate the Drug-Drug Interactions of Brivaracetam and Ethanol in Healthy Male Subjects

Start date: September 2012
Phase: Phase 1
Study type: Interventional

To evaluate if Brivaracetam (BRV) influences the psychomotor and cognitive impairing effects of Ethanol

NCT ID: NCT01708616 Completed - Healthy Volunteer Clinical Trials

A Study of the Combination of Multiple Doses of RO5285119 With a Single Dose of Risperidone in Healthy Volunteers

Start date: November 2012
Phase: Phase 1
Study type: Interventional

This single-center, randomized, double-blind, two-period crossover study will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamic effects of the combination of multiple doses of RO5285119 with a single dose of risperidone in healthy volunteers. Subjects will be randomized to one of 4 treatment sequences of two periods to receive multiple doses of RO5285119 plus a single dose of risperidone or risperidone placebo or multiple doses of RO5285119 placebo plus a single dose of risperidone or risperidone placebo, with a washout period of approximately 3 weeks between treatment periods. Anticipated time on study is up to 12 weeks (from screening through study completion).

NCT ID: NCT01708408 Active, not recruiting - Healthy Volunteers Clinical Trials

The MURDOCK Study Registry and Biorepository Horizon 1.5

MURDOCK
Start date: February 2009
Phase:
Study type: Observational

The MURDOCK Study Community Registry and Biorepository (Horizon 1.5) aims to create a large-scale community registry and biorepository that can be used as a vehicle for future health services, epidemiologic, clinical trials and other omics-related research.

NCT ID: NCT01704222 Completed - Healthy Volunteers Clinical Trials

Epidemiology of Human Cytomegalovirus Excretion in the Saliva of Children Attending Nursery in France

CrèchMV
Start date: September 2009
Phase: N/A
Study type: Observational

Direct DNA amplification, viral isolation and specific antibody measurement in saliva from children attending nursery in France Sample collection will be done by the pediatrician the nurse, or one of the authorized investigators of the study.

NCT ID: NCT01704040 Completed - Clinical trials for Healthy Volunteers and Asthma

A Study of CNTO 3157 in Healthy Normal and Asthmatic Participants Inoculated With Human Rhinovirus Type 16

Start date: October 2012
Phase: Phase 1
Study type: Interventional

The main purposes of this study are to evaluate the safety (Parts 1 and 2) and efficacy (Part 2) of pretreatment with CNTO 3157 in healthy adult and asthmatic adult participants before and after intranasal (into the nose) inoculation with human rhinovirus type 16 (HRV-16).

NCT ID: NCT01702649 Completed - Healthy Volunteers Clinical Trials

Safety, Tolerability, Pharmacokinetics of Intravenous RPX2003 (Biapenem) in Healthy Adult Subjects

Start date: August 2012
Phase: Phase 1
Study type: Interventional

RPX2003 (biapenem) is being studied in combination with a beta-lactamase inhibitor to treat bacterial infections, including those due to multi-drug resistant bacteria.

NCT ID: NCT01702506 Completed - Healthy Volunteers Clinical Trials

Evaluation Of The Potential Effect That The Administration Of Food Or Antacid Medication May Have In The Oral Absorption Of Dacomitinib (PF-00299804)

Start date: October 2012
Phase: Phase 1
Study type: Interventional

Evaluation of the potential effect that the administration of food or antacid medication may have in the oral absorption of dacomitinib relative to the administration of dacomitinib in absence of food or antacid medication

NCT ID: NCT01701739 Completed - Healthy Volunteer Clinical Trials

A Pharmacokinetics Study of Aleglitazar in Combination With Digoxin in Healthy Volunteers

Start date: October 2012
Phase: Phase 1
Study type: Interventional

This open-label, two-period, fixed-sequence study will investigate the pharmacokinetics and safety of multiple doses of aleglitazar on a single dose of digoxin in healthy volunteers. In period 1, volunteers will receive a single dose of digoxin, in period 2 volunteers will receive multiple doses of aleglitazar and a single dose of digoxin. The anticipated time on study treatment is one month.

NCT ID: NCT01701089 Completed - Clinical trials for Healthy Volunteer, Alzheimer's Disease

A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers

Start date: September 2012
Phase: Phase 1
Study type: Interventional

This open-label, multiple dose, parallel group study will assess the monoamine oxidase in the brain by in vivo positron emission tomography (PET) and safety of RO4602522 in patients with Alzheimer disease and in healthy volunteers. Patients and volunteers will receive multiple doses of RO4602522 and up to three injections of C11-L-deprenyl-D2 used in the PET.